Evidence map›Paper›PMID 32992491›Full record

ArticleInternational journal of molecular sciences2020

The Impact of Controlled Ovarian Stimulation Hormones on the Metabolic State and Endocannabinoid System of Human Cumulus Cells.

Valentina Notarstefano, Giorgia Gioacchini, Elisabetta Giorgini, Nina Montik, Andrea Ciavattini, Anna Rita Polidori, Fulvia Antonia Candela, Lisa Vaccari, Maurizio Cignitti, Oliana Carnevali

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.3field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Review
  3. Regulation and Role of Adiponectin Secretion in Rat Ovarian Granulosa Cells.International journal of molecular sciences · 2024
    Article
  4. Article
  5. Article
  6. Central and Local Modulators of Reproduction and Fertility: An Update.International journal of molecular sciences · 2022
    Article
  7. Article
  8. Article
  9. ATR-FTIR Analysis of Orthodontic InvisalignMaterials (Basel, Switzerland) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Valentina NotarstefanoDepartment of Life and Environmental Sciences, Università Politecnica delle Marche, Via Brecce Bianche, 60131 Ancona, Italy.ORCID 0000-0002-4651-6235
Giorgia GioacchiniDepartment of Life and Environmental Sciences, Università Politecnica delle Marche, Via Brecce Bianche, 60131 Ancona, Italy.
Elisabetta GiorginiDepartment of Life and Environmental Sciences, Università Politecnica delle Marche, Via Brecce Bianche, 60131 Ancona, Italy.
Nina MontikClinica Ostetrica Ginecologica, Università Politecnica delle Marche, Ospedale G. Salesi, Via F. Corridoni 11, 60121 Ancona, Italy.
Andrea CiavattiniClinica Ostetrica Ginecologica, Università Politecnica delle Marche, Ospedale G. Salesi, Via F. Corridoni 11, 60121 Ancona, Italy.
Anna Rita PolidoriCentro di Medicina della Riproduzione, Ospedale G. Salesi, Via F. Corridoni 11, 60123 Ancona, Italy.
Fulvia Antonia CandelaCentro di Medicina della Riproduzione, Ospedale G. Salesi, Via F. Corridoni 11, 60123 Ancona, Italy.
Lisa VaccariElettra Sincrotrone Trieste, SISSI Beamline, 34149 Basovizza, Trieste, Italy.
Maurizio CignittiClinica Ostetrica Ginecologica, Università Politecnica delle Marche, Ospedale G. Salesi, Via F. Corridoni 11, 60121 Ancona, Italy.
Oliana CarnevaliDepartment of Life and Environmental Sciences, Università Politecnica delle Marche, Via Brecce Bianche, 60131 Ancona, Italy.ORCID 0000-0001-5994-0572
Marche Polytechnic University · ITCentro Medicina della Riproduzione · ITElettra-Sincrotrone Trieste S.C.p.A. · IT

Funding

Università Politecnica delle Marche Fondo di Ateneo 2019 to O.C.
6 · The paper itself

Abstract

Different Follicle Stimulating Hormone (FSH) formulation and Luteinizing Hormone (LH) are used in Assisted Reproductive Technology (ART) to induce follicles development and oocytes maturation, but it is still under debate which protocol is to be preferred. In the present study, the different effects on cumulus cells (CCs) of three controlled ovarian stimulation (COS) protocols, based on urinary FSH, recombinant FSH, or human Menopausal Gonadotropin (hMG) administration, were assessed. CCs were obtained from 42 normal-responders women undergoing COS, randomly divided into three groups according to the used gonadotropin formulation. Differences were found in the expression of genes belonging to the endocannabinoid system (the receptors

Indexed as

AdultArachidonic AcidsCells, CulturedCohort StudiesCumulus CellsEndocannabinoidsFemaleFollicle Stimulating Hormone, HumanGene ExpressionHumansMenotropinsOocyte RetrievalOvulation InductionPolyunsaturated AlkamidesRecombinant ProteinsSignal TransductionanandamideArachidonic AcidsEndocannabinoidsFollicle Stimulating Hormone, Humanfollitropin betaMenotropinsPolyunsaturated AlkamidesRecombinant ProteinsUrofollitropinCOSendocannabinoidsFourier Transform InfraRed Microspectroscopygonadotropinslipid and carbohydrate metabolismoocyte maturation

Identifiers

PMID32992491
PMCPMC7583999
OpenAlexW3088507343

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.