ArticleAnesthesia progress2020
Pseudocholinesterase Deficiency Considerations: A Case Study.
Article in Anesthesia progress, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06217341 (Bispectral Index and Emergence Agitation in Spinal Surgeries), which is not on this map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Bispectral Index and Emergence Agitation in Spinal Surgeries
Who cites it
5 citing papers in PubMed, 11 citations in OpenAlex.
- Unexpected Prolonged Apnea Following Succinylcholine in a Medically Complex Patient: A Case Report.Cureus · 2026Article
- Delayed Recovery After General Anesthesia due to Undiagnosed Pseudocholinesterase Deficiency: A Case Report.Case reports in anesthesiology · 2026Article
- Pitfalls of electromyography (EMG) in parathyroidectomy: a case report of unrecognized pseudocholinesterase deficiency.Annals of translational medicine · 2025Article
- Genome-based newborn screening for severe childhood genetic diseases has high positive predictive value and sensitivity in a NICU pilot trial.American journal of human genetics · 2024Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pseudocholinesterase deficiency, sometimes called butyrylcholinesterase deficiency, is a rare disorder in which the neuromuscular blocking drugs succinylcholine and mivacurium cannot be metabolized properly in the blood plasma. This disorder can either be acquired as a result of certain comorbidities or it can be inherited genetically. Anesthesia providers must understand the pathophysiology of pseudocholinesterase deficiency and be prepared to safely and effectively manage patients who show signs and symptoms consistent with the disorder after the use of the indicated neuromuscular blocking drugs. This article summarizes the pharmacologic and physiologic data relevant to understanding the basic pathophysiology associated with pseudocholinesterase deficiency and illustrates a case study of a young woman suspected of having the disorder after a prolonged delay in emergence from general anesthesia.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.