Evidence map›Paper›PMID 32992115›Full record

ArticleBiomaterials2021

On-demand degradable embolic microspheres for immediate restoration of blood flow during image-guided embolization procedures.

Hyunjun Choi, Bongseo Choi, Bo Yu, Weiguo Li, Monica M Matsumoto, Kathleen R Harris, Robert J Lewandowski, Andrew C Larson, Samdeep K Mouli, Dong-Hyun Kim

Open access · greenAbstract read
In one paragraph

Article in Biomaterials, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.8field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 46 citations in OpenAlex.

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  10. Materials today. Bio · 2024
    Article
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  12. Temporary Embolic Agents.Seminars in interventional radiology · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Hyunjun ChoiDepartment of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA; Department of Bioengineering, University of Illinois at Chicago, Chicago, IL, 60607, USA.
Bongseo ChoiDepartment of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA.
Bo YuDepartment of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA.
Weiguo LiDepartment of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA.
Monica M MatsumotoDepartment of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA.
Kathleen R HarrisDepartment of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA.
Robert J LewandowskiDepartment of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA.
Andrew C LarsonDepartment of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA; Department of Bioengineering, University of Illinois at Chicago, Chicago, IL, 60607, USA; Department of Biomedical Engineering, McCormick School of Engineering, Evanston, IL, 60208, USA; Robert H. Lurie Comprehensive Cancer Center, Chicago, IL, 60611, USA.
Samdeep K MouliDepartment of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA.
Dong-Hyun KimDepartment of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA; Department of Bioengineering, University of Illinois at Chicago, Chicago, IL, 60607, USA; Department of Biomedical Engineering, McCormick School of Engineering, Evanston, IL, 60208, USA; Robert H. Lurie Comprehensive Cancer Center, Chicago, IL, 60611, USA. Electronic address: dhkim@northwestern.edu.
Northwestern University · USIndo-American Center · USMcCormick Theological Seminary · US

Funding

Catheter-Directed Image-Guided Delivery of Cytostatic and Cytotoxic Combination Therapy to Liver TumorsR01CA218659 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI KIM, DONG-HYUN · 2018 to 2022
$1.9M
Image-Guided Transcatheter Delivery of Natural Killer Cell Therapy Augmented with IFN-Gamma Eluting MicrospheresR01EB026207 · NIBIB · NORTHWESTERN UNIVERSITY AT CHICAGO · PI KIM, DONG-HYUN · 2018 to 2021
$1.4M
NCI NIH HHS R01 CA218659NIBIB NIH HHS R01 EB026207
6 · The paper itself

Abstract

Degradable embolic agents that provide transient arterial occlusion during embolization procedures have been of interest for many years. Ideally, embolic agents are visible with standard imaging modalities and offer on-demand degradability, permitting physicians to achieve desired arterial occlusion tailored to patient and procedure indication. Subsequent arterial recanalization potentially enhances the overall safety and efficacy of embolization procedures. Here, we report on-demand degradable and MRI-visible microspheres for embolotherapy. Embolic microspheres composed of calcium alginate and USPIO nanoclusters were synthesized with an air spray atomization and coagulation reservoir equipped with a vacuum suction. An optimized distance between spray nozzle and reservoir allowed uniform size and narrow size distribution of microspheres. The fabricated alginate embolic microspheres crosslinked with Ca

Indexed as

Embolization, TherapeuticAlginatesAnimalsArteriesHumansMagnetic Resonance ImagingMicrospheresRabbitsAlginatesEmbolic agentsEmbolizationEmbolotherapyInterventional radiologyOn-demand degradable microspheres

Identifiers

PMID32992115
PMCPMC7673262
OpenAlexW3088106952

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.