Evidence map›Paper›PMID 32991939›Full record

ArticleNeurotoxicology2020

AMPA receptor contribution to methylmercury-mediated alteration of intracellular Ca

Alexandra Colón-Rodríguez, Nicole M Colón-Carrión, William D Atchison

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neurotoxicology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. Effects of Zinc, Mercury, or Lead on [Neurochemical research · 2021
    Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Alexandra Colón-RodríguezDepartment of Pharmacology and Toxicology, College of Veterinary Medicine, Michigan State University, 1355 Bogue St., B338 Life Science Bldg., East Lansing, MI 48824, United States; Institute for Integrative Toxicology, College of Veterinary Medicine, Michigan State University, 1355 Bogue St., B338 Life Science Bldg., East Lansing, MI 48824, United States; Comparative Medicine and Integrative Biology Program, College of Veterinary Medicine, Michigan State University, 1355 Bogue St., B331 Life Science Bldg., East Lansing, MI 48824, United States. Electronic address: alexandracolonr@gmail.com.
Nicole M Colón-CarriónDepartment of Pharmacology and Toxicology, College of Veterinary Medicine, Michigan State University, 1355 Bogue St., B338 Life Science Bldg., East Lansing, MI 48824, United States. Electronic address: ncoloncarrion@email.arizona.edu.
William D AtchisonDepartment of Pharmacology and Toxicology, College of Veterinary Medicine, Michigan State University, 1355 Bogue St., B338 Life Science Bldg., East Lansing, MI 48824, United States; Institute for Integrative Toxicology, College of Veterinary Medicine, Michigan State University, 1355 Bogue St., B338 Life Science Bldg., East Lansing, MI 48824, United States; Comparative Medicine and Integrative Biology Program, College of Veterinary Medicine, Michigan State University, 1355 Bogue St., B331 Life Science Bldg., East Lansing, MI 48824, United States. Electronic address: atchiso1@msu.edu.
Michigan State University · US

Funding

Environmental Metals, Excitotoxicity and ALSR01ES024064 · NIEHS · MICHIGAN STATE UNIVERSITY · PI ATCHISON, WILLIAM D · 2015 to 2019
$2.4M
NIEHS NIH HHS R01 ES024064
6 · The paper itself

Abstract

α motor neurons (MNs) are a target of the environmental neurotoxicant methylmercury (MeHg), accumulating MeHg and subsequently degenerating. In mouse spinal cord MN cultures, MeHg increased intracellular Ca

Indexed as

Calcium SignalingCalciumCell DeathCell LineExcitatory Amino Acid AntagonistsHumansInduced Pluripotent Stem CellsMethylmercury CompoundsMotor NeuronsNeural Stem CellsReceptors, AMPACalciumExcitatory Amino Acid Antagonistsmethylmercuric chlorideMethylmercury CompoundsReceptors, AMPAAMPA receptorGlutamateIntracellular calciumIon channelMethylmercuryMotor neurons

Identifiers

PMID32991939
PMCPMC7708444
OpenAlexW3090389535

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.