Evidence map›Paper›PMID 32991827›Full record

ReviewGut microbes2020

Relationship between gut environment, feces-to-food ratio, and androgen deficiency-induced metabolic disorders.

Naoki Harada, Yukari Minami, Kazuki Hanada, Ryo Hanaoka, Yasuyuki Kobayashi, Takeshi Izawa, Takashi Sato, Shigeaki Kato, Hiroshi Inui, Ryoichi Yamaji

Open access · goldAbstract readReview
In one paragraph

Review in Gut microbes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Review
  8. Article
  9. Foods (Basel, Switzerland) · 2022
    Article
  10. Article
  11. Effects ofFrontiers in endocrinology · 2022
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Naoki HaradaDivision of Applied Life Sciences, Graduate School of Life and Environmental Sciences, Osaka Prefecture University , Osaka, Japan.ORCID 0000-0003-3846-388X
Yukari MinamiDivision of Applied Life Sciences, Graduate School of Life and Environmental Sciences, Osaka Prefecture University , Osaka, Japan.
Kazuki HanadaDivision of Applied Life Sciences, Graduate School of Life and Environmental Sciences, Osaka Prefecture University , Osaka, Japan.
Ryo HanaokaDivision of Applied Life Sciences, Graduate School of Life and Environmental Sciences, Osaka Prefecture University , Osaka, Japan.
Yasuyuki KobayashiDivision of Applied Life Sciences, Graduate School of Life and Environmental Sciences, Osaka Prefecture University , Osaka, Japan.
Takeshi IzawaDivision of Veterinary Science, Graduate School of Life and Environmental Sciences, Osaka Prefecture University , Osaka, Japan.
Takashi SatoInstitute for Molecular and Cellular Regulation, Gunma University , Maebashi, Japan.
Shigeaki KatoGraduate School of Science and Engineering, Iryo Sosei University , Fukushima, Japan.ORCID 0000-0002-5564-1695
Hiroshi InuiDivision of Clinical Nutrition, Graduate School of Comprehensive Rehabilitation, Osaka Prefecture University , Osaka, Japan.
Ryoichi YamajiDivision of Applied Life Sciences, Graduate School of Life and Environmental Sciences, Osaka Prefecture University , Osaka, Japan.
Osaka Prefecture University · JPGunma University · JPIRYO Sosei University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Androgen action generates sex-related differences that include changes in the gut microbiota composition. Hypoandrogenism and hyperandrogenism in males and females, respectively, are associated with the prevalence of metabolic disorders. Our recent work showed that male androgen receptor knockout (ARKO) mice developed high-fat diet (HFD)-dependent sarcopenic abdominal obesity, hyperglycemia, and hepatic steatosis, leading to early death. The ARKO mice also exhibited alterations in intestinal microbiota but did not experience metabolic abnormalities when administered with antibiotics. Here, we show that time-dependent changes in feed efficiency (ratio of body weight gain to food intake) and weight of dried feces-to-food ratio could be good markers for changes in gut microbiota.

Indexed as

Gastrointestinal MicrobiomeAndrogensAnimalsEatingFecesHumansMetabolic DiseasesReceptors, AndrogenAndrogensReceptors, AndrogenApparent digestibility coefficientsfecesFirmicutes/Bacteroidetesgut microfloralongevitymetabolic syndromesarcopenic obesitystooltestosteronetype 2 diabetes mellitus (T2DM)

Identifiers

PMID32991827
PMCPMC7781658
OpenAlexW3090322925

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.