Evidence map›Paper›PMID 32991629›Full record

ArticlePloS one2020

Association of macular choroidal thickness with optical coherent tomography morphology in patients with idiopathic epiretinal membrane.

I-Mo Fang, Li-Li Chen

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Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

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11citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Predictors of two-year visual outcomes after surgery for stage 3-4 epiretinal membrane: role of baseline vision and early retinal microstructural recovery.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
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4 · The record

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5 · Who and what money

Authors and funding

2 authors.

I-Mo FangDepartment of Ophthalmology, Taipei City Hospital Zhongxiao Branch, Taipei, Taiwan.ORCID 0000-0001-6360-7588
Li-Li ChenDepartment of Ophthalmology, Taipei City Hospital Zhongxiao Branch, Taipei, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo compare macular choroidal thickness of idiopathic epiretinal membrane (ERM) and fellow eyes, and before and after vitrectomy in terms of the morphological features on spectral-domain optical coherent tomography (SD-OCT).

methodsEighty-four patients with unilateral idiopathic ERM were involved. Patients were categorized into: Group 1, ERM without membrane contraction; Group 2, ERM with membrane contraction and retinal folding; and Group 3, ERM with membrane contraction and macular edema. Twenty-two patients received surgical removal of ERM. Choroidal thickness was compared between ERM and fellow eyes, and before and after treatment.

resultsMean choroidal thickness was significantly greater in ERM eyes than in fellow eyes (234.4 ± 22.5 vs 220.6 ± 20.8 μm; P<0.01). Group 1 (n = 20) showed no significant difference in choroidal thickness between ERM and fellow eyes. Eyes in Group 2 (n = 27) and Group 3 (n = 37) showed statistically significant differences in mean choroidal thickness between ERM and fellow eyes (229.6 ± 23.8 vs 220.8 ± 19.6 μm; 242.6 ± 27.8 vs 221.0 ± 21.8 μm, respectively; P<0.05). In Group 2 (n = 8) and Group 3 (n = 16), choroidal thickness in ERM eyes decreased significantly at 1 month and 6 months after surgery, compared with that before surgery (P<0.05 for all comparisons).

conclusionsMembrane contraction contributed to the increase in choroidal thickness in idiopathic ERM patients. This finding may help to elucidate the pathophysiologic features of idiopathic ERM as well as the response to treatment in these patients.

Indexed as

Tomography, Optical CoherenceAdultAgedAged, 80 and overChoroidEpiretinal MembraneFemaleHumansMacula LuteaMaleMiddle Aged

Identifiers

PMID32991629
PMCPMC7523999

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.