Evidence map›Paper›PMID 32991152›Full record

ArticleJournal of the American Chemical Society2020

Synthetic, Mechanistic, and Biological Interrogation of

Robert M Demoret, Meghan A Baker, Masaki Ohtawa, Shuming Chen, Ching Ching Lam, Sophia Khom, Marisa Roberto, Stefano Forli, Kendall N Houk, Ryan A Shenvi

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Nano-Ayurvedic Medicine Approaches UsingNanotechnology, science and applications · 2024
    Article
  13. Neurotrophic Natural Products.Progress in the chemistry of organic natural products · 2024
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Recent progress in alkynylation with hypervalent iodine reagents.Chemical communications (Cambridge, England) · 2023
    Review
  19. Synthesis of Cycloheptatriene-Containing Azetidine Lactones.The Journal of organic chemistry · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Robert M DemoretDepartment of Chemistry, Scripps Research, La Jolla, California 92037, United States.
Meghan A BakerDepartment of Chemistry, Scripps Research, La Jolla, California 92037, United States.
Masaki OhtawaDepartment of Chemistry, Scripps Research, La Jolla, California 92037, United States.ORCID 0000-0001-7129-012X
Shuming ChenDepartment of Chemistry and Biochemistry, University of California at Los Angeles, Los Angeles, California 90095, United States.ORCID 0000-0003-1897-2249
Ching Ching LamDepartment of Chemistry and Biochemistry, University of California at Los Angeles, Los Angeles, California 90095, United States.
Sophia KhomDepartments of Molecular Medicine and Neuroscience, Scripps Research, La Jolla, California 92037, United States.ORCID 0000-0003-3567-8973
Marisa RobertoDepartments of Molecular Medicine and Neuroscience, Scripps Research, La Jolla, California 92037, United States.
Stefano ForliDISCoBio, Scripps Research, La Jolla, California 92037, United States.ORCID 0000-0002-5964-7111
Kendall N HoukDepartment of Chemistry and Biochemistry, University of California at Los Angeles, Los Angeles, California 90095, United States.ORCID 0000-0002-8387-5261
Ryan A ShenviDepartment of Chemistry, Scripps Research, La Jolla, California 92037, United States.ORCID 0000-0001-8353-6449

Funding

Viral Vector CoreP60AA006420 · NIAAA · SCRIPPS RESEARCH INSTITUTE, THE · PI MARISA ROBERTO · 2003 to 2026
$46.3M
Unusual Pharmacophores and New Tools for Cross-CouplingR35GM122606 · NIGMS · SCRIPPS RESEARCH INSTITUTE, THE · PI Ryan Ashok Shenvi · 2017 to 2026
$7.1M
Regulation of Ethanol Effects on Synaptic TransmissionR01AA015566 · NIAAA · SCRIPPS RESEARCH INSTITUTE, THE · PI ROBERTO, MARISA · 2006 to 2019
$4.6M
NIAAA NIH HHS P60 AA006420NIAAA NIH HHS R01 AA015566NIGMS NIH HHS R35 GM122606
6 · The paper itself

Abstract

Here we interrogate the structurally dense (1.64 mcbits/Å

Indexed as

BromidesCyclopentanesFuransGABA-A Receptor AntagonistsGinkgo bilobaGinkgolidesIsotope LabelingLactonesMolecular ConformationOxidation-ReductionStereoisomerismbilobalideBromidesCyclopentanesFuransGABA-A Receptor AntagonistsGinkgolidesLactones

Identifiers

PMID32991152
PMCPMC7727090

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.