ArticleACS chemical neuroscience2020
Biochemical Characterization of Mouse Retina of an Alzheimer's Disease Model by Raman Spectroscopy.
Article in ACS chemical neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.
- Accuracy of Raman spectroscopy in the diagnosis of Alzheimer's disease.Frontiers in psychiatry · 2023Pooled it
- Label-free in vivo molecular profiling of the human retina by non-resonant Raman spectroscopy.Communications biology · 2026Article
- Machine Learning Interpretation of Optical Spectroscopy Using Peak-Sensitive Logistic Regression.ACS nano · 2025Article
- Development of a label-free, functional, molecular and structural imaging system combining optical coherence tomography and Raman spectroscopy for in vivo measurement of rat retina.Biomedical optics express · 2025Article
- Imaging the eye as a window to brain health: frontier approaches and future directions.Journal of neuroinflammation · 2024Review
- Clearance of interstitial fluid (ISF) and CSF (CLIC) group-part of Vascular Professional Interest Area (PIA), updates in 2022-2023. Cerebrovascular disease and the failure of elimination of Amyloid-β from the brain and retina with age and Alzheimer's disease: Opportunities for therapy.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Review
- Current Trends of Raman Spectroscopy in Clinic Settings: Opportunities and Challenges.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Review
- Harnessing the power of Raman spectroscopic imaging for ophthalmology.Frontiers in chemistry · 2023Review
- Review: Emerging Eye-Based Diagnostic Technologies for Traumatic Brain Injury.IEEE reviews in biomedical engineering · 2023Review
- Raman Spectroscopy on Brain Disorders: Transition from Fundamental Research to Clinical Applications.Biosensors · 2022Review
- From Research to Diagnostic Application of Raman Spectroscopy in Neurosciences: Past and Perspectives.Free neuropathology · 2022Article
- The Progress of Label-Free Optical Imaging in Alzheimer's Disease Screening and Diagnosis.Frontiers in aging neuroscience · 2021Review
Corrections and comments
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Authors and funding
9 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The presence of biomarkers characteristic for Alzheimer's disease in the retina is a controversial topic. Raman spectroscopy offers information on the biochemical composition of tissues. Thus, it could give valuable insight into the diagnostic value of retinal analysis. Within the present study, retinas of a double transgenic mouse model, that expresses a chimeric mouse/human amyloid precursor protein and a mutant form of human presenilin 1, and corresponding control group were subjected to
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.