Evidence map›Paper›PMID 32990927›Full record

ArticleCanadian journal of public health = Revue canadienne de sante publique2020

Sex, gender and COVID-19: a call to action.

Sofia B Ahmed, Sandra M Dumanski

Registry-linked trialOpen access · bronzeAbstract read
In one paragraph

Article in Canadian journal of public health = Revue canadienne de sante publique, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04970719 (The Efficacy of Baricitinib Plus Remdesivir Compared to Dexamethasone Plus Remdesivir in Hospitalised COVID-19 Patients With Diabetes Mellitus), which is not on this map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
5.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04970719 phase3withdrawnnot on this mapstarted 2021, after this paper: background citation

The Efficacy of Baricitinib Plus Remdesivir Compared to Dexamethasone Plus Remdesivir in Hospitalised COVID-19 Patients With Diabetes Mellitus

TypeinterventionalSponsorBangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic DisordersRan2021 to 2021Enrolled0ConditionsCOVID-19 PneumoniaArmsBaricitinib, Dexamethasone, Remdesivir
3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it, 65 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Observational
  4. Article
  5. Article
  6. Nursing Students' Perception about Gender Inequalities Presented on Social Networks: A Qualitative Study.International journal of environmental research and public health · 2023
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  17. High concordance in SARSCoV-2 detection between automated (Journal of public health in Africa · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Sofia B AhmedCumming School of Medicine, University of Calgary, Calgary, Alberta, Canada. sofia.ahmed@albertahealthservices.ca.ORCID 0000-0003-3000-2229
Sandra M DumanskiCumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
University of Calgary · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An understanding of the influence of sex (biological attributes) and gender (socially constructed roles, behaviours, expressions, identities) factors on the risk of infection, hospitalization and death is of urgent importance in the COVID-19 pandemic response effort. Despite similar global rates of infection with Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2, the virus responsible for the COVID-19 pandemic), hospitalizations and mortality are higher in men than in women. Females may be less vulnerable to viral infection due to sex-based differences in immune responses and renin-angiotensin system activity. The response and side effects of currently studied potential therapies for COVID-19, such as hydroxychloroquine, likely differ by sex. Women form the majority of the health care workforce and a uniform approach to sizing of personal protective equipment may provide differing levels of protection from viral infection to health care workers of varying shapes and sizes. Important gender differences exist in the response to public health measures to prevent and contain spread of COVID-19, as well as presentation for testing and medical care, which may inadvertently propagate viral spread. Targeted approaches that consider both sex and gender, as well as measures of intersectionality, are urgently needed in the response efforts against COVID-19.

Indexed as

Gender IdentityPandemicsSex FactorsCanadaCOVID-19FemaleHealth BehaviorHumansMalePersonal Protective EquipmentCOVID-19GenderInfectionMortalityPolicySex

Identifiers

PMID32990927
PMCPMC7523484
OpenAlexW3091563171

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.