Evidence map›Paper›PMID 32990593›Full record

ArticleeLife2020

Feed-forward recruitment of electrical synapses enhances synchronous spiking in the mouse cerebellar cortex.

Andreas Hoehne, Maureen H McFadden, David A DiGregorio

Open access · goldAbstract read
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
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  5. Article
  6. Article
  7. Review
  8. Excitation and Inhibition Delays within a Feedforward Inhibitory Pathway Modulate Cerebellar Purkinje Cell Output in Mice.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023
    Article
  9. Article
  10. Article
  11. The Cerebellar Cortex.Annual review of neuroscience · 2022
    Review
  12. Article
  13. Review
  14. On the Diverse Functions of Electrical Synapses.Frontiers in cellular neuroscience · 2022
    Review
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Andreas HoehneLaboratory of Synapse and Circuit Dynamics, Institut Pasteur, Paris Cedex, France.
Maureen H McFaddenLaboratory of Synapse and Circuit Dynamics, Institut Pasteur, Paris Cedex, France.ORCID 0000-0001-9770-7069
David A DiGregorioLaboratory of Synapse and Circuit Dynamics, Institut Pasteur, Paris Cedex, France.ORCID 0000-0002-6417-4566
Institut Pasteur · FR

Funding

Agence Nationale de la Recherche ANR-13-BSV4-0016Agence Nationale de la Recherche ANR-17-CE16-0019Agence Nationale de la Recherche ANR-17-CE16-0026Agence Nationale de la Recherche ANR-18-CE16-0018Agence Nationale de la Recherche ANR-2010-BLANC-1411
6 · The paper itself

Abstract

In the cerebellar cortex, molecular layer interneurons use chemical and electrical synapses to form subnetworks that fine-tune the spiking output of the cerebellum. Although electrical synapses can entrain activity within neuronal assemblies, their role in feed-forward circuits is less well explored. By combining whole-cell patch-clamp and 2-photon laser scanning microscopy of basket cells (BCs), we found that classical excitatory postsynaptic currents (EPSCs) are followed by GABA

Indexed as

Action PotentialsAnimalsCerebellar CortexElectrical SynapsesElectrophysiologyExcitatory Postsynaptic PotentialsFeedback, PhysiologicalFemaleInterneuronsMaleMiceReceptors, GABA-AReceptors, GABA-Acerebellumelectrical synapsesfeed-forward circuitinterneuronsmouseneurosciencesynchrony

Identifiers

PMID32990593
PMCPMC7524550
OpenAlexW3091151162

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.