Evidence map›Paper›PMID 32990236›Full record

ArticleNan fang yi ke da xue xue bao = Journal of Southern Medical University2020

[Anti-scarring effect of rapamycin following filtering surgery in rabbit eyes].

Xue Tai, Ying Shen, Haixia Zhao, Zhaoge Wang, Wenying Guan, Xin Kang, Wenqi Guo

Open access · greenAbstract read
In one paragraph

Article in Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact, top 85% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 1 citations in OpenAlex.

  1. Pooled it
  2. [Silybin inhibits fibrosis after glaucoma filtration surgery in rabbits by promoting fibroblast autophagy].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Xue TaiCenter of Myopia, Affiliated Hospital of Inner Mongolia Medical University, Hohhot 010050, China.
Ying ShenCenter of Myopia, Affiliated Hospital of Inner Mongolia Medical University, Hohhot 010050, China.
Haixia ZhaoCenter of Myopia, Affiliated Hospital of Inner Mongolia Medical University, Hohhot 010050, China.
Zhaoge WangCenter of Myopia, Affiliated Hospital of Inner Mongolia Medical University, Hohhot 010050, China.
Wenying GuanCenter of Myopia, Affiliated Hospital of Inner Mongolia Medical University, Hohhot 010050, China.
Xin KangCenter of Myopia, Affiliated Hospital of Inner Mongolia Medical University, Hohhot 010050, China.
Wenqi GuoDepartment of Emergency Medicine, Second Affiliated Hospital of Inner Mongolia Medical University, Hohhot 010030, China.
Inner Mongolia Medical University · CNSecond Affiliated Hospital of Inner Mongolia Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo study the effect of rapamycin on scar formation in rabbit eyes following filtering operation and explore the possible mechanism.

methodsNinety-six healthy adult rabbits were subjected to trabeculectomy of the left eye and subsequently randomly divided into 4 groups (

resultsIn the first, second and third weeks after the operation, the rate of functional follicle formation was significantly higher in the 3 rapamycin groups than in the control group (

conclusionsRapamycin can inhibit hyperplasia of the filtering passage tissue, helps to preserve the functional filtering blebs and prolong their life span, and induces apoptosis of RTFS.

Indexed as

GlaucomaAnimalsCicatrixEyeOphthalmologic Surgical ProceduresRabbitsSirolimusSirolimusglaucoma filtering operationproliferating cell nuclear antigenrapamycinsignal transductionα-smooth muscle actin

Identifiers

PMID32990236
PMCPMC7544582
OpenAlexW3090365611

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.