Evidence map›Paper›PMID 32990229›Full record

ArticleNan fang yi ke da xue xue bao = Journal of Southern Medical University2020

[Epigallocatechin gallate induces

Mingcai Wu, Ming Jiang, Mengya Xue, Qing Li, Bing Cheng, Mengzhu Huang, Lei Xu, Yao Zhang

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Mingcai WuDepartment of Biochemistry and Molecular Biology, Wannan Medical College, Wuhu 241002, China.
Ming JiangWuhu Second Sanatorium for Retired Cadres, Anhui Provincial Military Command, Wuhu 241002, China.
Mengya XueDepartment of Biochemistry and Molecular Biology, Wannan Medical College, Wuhu 241002, China.
Qing LiDepartment of Biochemistry and Molecular Biology, Wannan Medical College, Wuhu 241002, China.
Bing ChengDepartment of Biochemistry and Molecular Biology, Wannan Medical College, Wuhu 241002, China.
Mengzhu HuangDepartment of Biochemistry and Molecular Biology, Wannan Medical College, Wuhu 241002, China.
Lei XuDepartment of Biochemistry and Molecular Biology, Wannan Medical College, Wuhu 241002, China.
Yao ZhangDepartment of Biochemistry and Molecular Biology, Wannan Medical College, Wuhu 241002, China.
Wannan Medical College · CNWuhu Institute of Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the mechanism by which epigallocatechin gallate (EGCG) induces

methodsKG-1 and THP-1 cells treated with 25, 50, 75, 100 or 150 μg/mL EGCG for 48 h were examined for

resultsEGCG dose-dependently reversed hypermethylation of

conclusionsEGCG reduces hypermethylation of

Indexed as

Leukemia, Myeloid, AcuteAntigens, CDApoptosisCadherin 5CadherinsCatechinCyclin-Dependent Kinase Inhibitor p21DemethylationHumansSignal TransductionTumor Suppressor Protein p53Antigens, CDCadherin 5CadherinsCatechinCDKN1A protein, humanCyclin-Dependent Kinase Inhibitor p21epigallocatechin gallateTP53 protein, humanTumor Suppressor Protein p53acute myleoid leukemiaCHD5 geneepigallocatechin gallatemethylationp19Arf-p53-p21Cip1 signaling pathway

Identifiers

PMID32990229
PMCPMC7544577
OpenAlexW3090171023

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.