Evidence map›Paper›PMID 32990145›Full record

ReviewOrbit (Amsterdam, Netherlands)2021

Advancements in the repair of large upper eyelid defects: A 10-year review.

Erin Jennings, Mark Krakauer, William R Nunery, Vinay Kumar Aakalu

Abstract readReview
In one paragraph

Review in Orbit (Amsterdam, Netherlands), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Rising challenges in dermatosurgery: Cutler-Beard flap for total upper eyelid defect after squamous cell carcinoma.Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG · 2025
    Article
  5. Review
  6. Review
  7. "Lid Switch Flap" for Subtotal Upper Eyelid Reconstruction: Where the Flap Pedicle and the Point of Rotation Should be Located.Indian journal of plastic surgery : official publication of the Association of Plastic Surgeons of India · 2023
    Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Erin JenningsDepartment of Ophthalmology, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, USA.
Mark KrakauerDepartment of Ophthalmology, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, USA.ORCID 0000-0002-2798-7218
William R NuneryDepartment of Ophthalmology, University of Louisville, Louisville, KY, USA.
Vinay Kumar AakaluDepartment of Ophthalmology and Visual Sciences, College of Medicine, University of Illinois at Chicago, Chicago, USA.

Funding

Translational Core for Therapeutic and Diagnostic DevelopmentP30EY001792 · NEI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI YAO, XINCHENG · 1985 to 2025
$14.8M
NEI NIH HHS P30 EY001792
6 · The paper itself

Abstract

purposeThe reconstruction of large (>50%) upper eyelid margin defects can be technically challenging, with multiple approaches described in the literature. We sought to review the recent literature for new techniques or modifications to existing techniques.

methodsWe conducted a Pubmed search for technique papers on the reconstruction of large upper eyelid defects published within the past ten years with a minimum of four patients.

resultsWe identified ten articles, and divided them into techniques that use a bridging flap from the lower eyelid and those that do not. The number of upper eyelids repaired in each article ranged from 4 to 17. Most techniques could be considered either a modification of the Cutler-Beard technique or a novel anterior lamella flap laid over a graft for the posterior lamella. Postoperative complications included upper or lower eyelid cicatricial retraction, trichiasis, entropion, and lagophthalmos.

conclusionsSurgeons continue to innovate for this challenging reconstructive surgery. Overall, the trend was to use a graft, most commonly tarsoconjunctiva from the contralateral upper lid, to replace the posterior lamella, and a skin flap, from the lower eyelid or from the adjacent periorbital area, to replace the anterior lamella. Bridging techniques utilized the skin; the skin, orbicularis, and conjunctiva; or a tarsoconjunctival flap from the lower eyelid. Non-bridging techniques generally used a tarsoconjunctival or substitute graft for the posterior lamella, and a skin flap for the anterior lamella.

Indexed as

EntropionEyelid DiseasesEyelid NeoplasmsPlastic Surgery ProceduresEyelidsHumansSkin TransplantationSurgical FlapsEyelid tumorsurgical techniquestarsoconjunctival upper eyelid flapupper eyelid graftupper eyelid reconstruction

Identifiers

PMID32990145
PMCPMC8005505

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.