ArticleMagnetic resonance in medicine2021
3D UTE bicomponent imaging of cortical bone using a soft-hard composite pulse for excitation.
Article in Magnetic resonance in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Bicomponent Mapping of Cortical Bone Using a New Interleaved UTE Imaging Sequence.Magnetic resonance in medicine · 2026Article
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7 authors.
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Abstract
purposeTo evaluate 3D UTE bicomponent imaging of cortical bone ex vivo and in vivo using a newly designed soft-hard composite pulse for excitation.
methodsChemical shift artifacts, presenting as fat-water oscillation or combination-induced signal oscillation, significantly reduce the accuracy of quantitative UTE bicomponent analysis of cortical bone. To achieve fat suppression for more reliable bicomponent analysis, a newly developed soft-hard excitation pulse was used with UTE imaging and compared with a single rectangular pulse excitation without and with a conventional fat saturation (FatSat) module. These 3 sequences were applied to 8 bovine bone samples without marrow fat, 3 bovine bone samples with marrow fat, and tibial midshafts of 5 healthy human volunteers. Bicomponent analyses were performed in both ex vivo and in vivo studies.
resultsThe soft-hard pulse provided comparable fat suppression, but much reduced bone signal attenuation compared with the FatSat module. Better bicomponent
conclusionThe 3D UTE sequence with a new soft-hard excitation pulse allows more reliable bicomponent imaging of cortical bone.
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