Evidence map›Paper›PMID 32989731›Full record

ArticleJournal of the American Geriatrics Society2021

Geriatric Syndromes and Atrial Fibrillation: Prevalence and Association with Anticoagulant Use in a National Cohort of Older Americans.

Sachin J Shah, Margaret C Fang, Sun Y Jeon, Steven E Gregorich, Kenneth E Covinsky

Open access · greenAbstract read
In one paragraph

Article in Journal of the American Geriatrics Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 37 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Sachin J ShahDivision of Hospital Medicine, University of California, San Francisco, San Francisco, California, USA.
Margaret C FangDivision of Hospital Medicine, University of California, San Francisco, San Francisco, California, USA.
Sun Y JeonDivision of Geriatrics, University of California, San Francisco, San Francisco, California, USA.
Steven E GregorichDivision of General Internal Medicine, University of California, San Francisco, San Francisco, California, USA.
Kenneth E CovinskyDivision of Geriatrics, University of California, San Francisco, San Francisco, California, USA.
University of California, San Francisco · USSan Francisco General Hospital · US

Funding

VARC CoreP30AG044281 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Louise C. Walter · 2013 to 2026
$19.9M
Institutional Career Development Core SupplementKL2TR001870 · NCATS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KANAYA, ALKA M., SARKAR, URMIMALA · 2016 to 2025
$19.7M
RESOURCE CENTER FOR AGING RESEARCH IN DIVERSE POPULATIONP30AG015272 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Torsten Brian Neilands · 1997 to 2026
$19.5M
Unnecessary and Harmful Medication Use in Older Adults with DementiaP01AG066605 · NIA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI KENNETH E. COVINSKY · 2020 to 2026
$17.7M
Use and outcomes of anticoagulants for the treatment and prevention of thrombosis among hospitalized patientsK24HL141354 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FANG, MARGARET C. · 2018 to 2022
$731k
NCATS NIH HHS KL2 TR001870NCATS NIH HHS KL2TR001870NHLBI NIH HHS K24 HL141354NHLBI NIH HHS K24HL141354NIA NIH HHS P01 AG066605NIA NIH HHS P30 AG015272NIA NIH HHS P30AG015272NIA NIH HHS P30 AG044281NIA NIH HHS P30AG044281
6 · The paper itself

Abstract

backgroundAlthough guidelines recommend focusing primarily on stroke risk to recommend anticoagulants in atrial fibrillation (AF), physicians report that geriatric syndromes (e.g., falls and disability) are important when considering anticoagulants. Little is known about the prevalence of geriatric syndromes in older adults with AF or the association with anticoagulant use.

methodsWe performed a cross-sectional analysis of the 2014 Health and Retirement Study, a nationally representative study of older Americans. Participants were asked questions to assess domains of aging, including function, cognition, and medical conditions. We included participants 65 years and older with 2 years of continuous Medicare enrollment who met AF diagnosis criteria by claims codes. We examined five geriatric syndromes: one or more falls within the last 2 years, receiving help with activities of daily living (ADLs) or instrumental ADLs (IADL), experienced incontinence, and cognitive impairment. We determined the prevalence of geriatric syndromes and their association with anticoagulant use, adjusting for ischemic stroke risk (i.e., CHA

resultsIn this study of 779 participants with AF (median age = 80 years; median CHA

conclusionMost older adults with AF had at least one geriatric syndrome, and geriatric syndromes were associated with reduced anticoagulant use. The high prevalence of geriatric syndromes may explain the lower than expected anticoagulant use in older adults.

Indexed as

Atrial FibrillationIschemic StrokeAccidental FallsAged, 80 and overAnticoagulantsCross-Sectional StudiesDrug UtilizationFemaleGeriatric AssessmentHumansMaleMultiple Chronic ConditionsPersons with DisabilitiesPrevalenceRisk AdjustmentRisk AssessmentAnticoagulantsanticoagulantsatrial fibrillationepidemiologygeriatric syndromes

Identifiers

PMID32989731
PMCPMC8174581
OpenAlexW3089714455

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.