ArticleInternational urology and nephrology2021
Inhibitory effects of a minimally invasive implanted tibial nerve stimulation device on non-nociceptive bladder reflexes in cats.
Article in International urology and nephrology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed, 8 citations in OpenAlex.
- Tibial nerve stimulation for overactive bladder: a literature review of stimulation parameters.Translational andrology and urology · 2026Review
- Effects of pelvic floor electrical stimulation with an implantable device at different frequencies on stress urinary incontinence in rats.European journal of medical research · 2025Article
- The mechanism of action of neuromodulation in the treatment of overactive bladder.Nature reviews. Urology · 2025Review
- A potential therapeutic strategy using a miniature, implantable, wireless nerve stimulation device for treating stress urinary incontinence in rats.International urology and nephrology · 2025Article
- Effects of different pulse widths on acute tibial nerve stimulation for overactive bladder in cats.European journal of medical research · 2025Article
- Safety and Effectiveness of Nustim System Implantation in Dogs.Bladder (San Francisco, Calif.) · 2022Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
objectiveThe present study investigated the inhibitory effects of a novel minimally invasive implanted tibial nerve stimulation device on non-nociceptive bladder reflexes in cats. MATERIALS AND
methodsA wireless minimally invasive implanted nerve stimulator was implanted adjacent to the left tibial nerve in seven cats. Multiple cystometrograms (CMGs) were obtained to determine the inhibitory effects of tibial nerve stimulation (TNS) at different frequencies and intensities on the micturition reflex by infusing normal saline (NS).
resultsTNS at 6 Hz did not significantly change the bladder capacity (BC) compared to the control level at the intensity threshold (T), while TNS significantly (P < 0.05) increased the BC to 158.89 ± 20.57% of the control level at 2 T. When stimulated at 15 Hz, TNS did not significantly (P > 0.05) change the BCs at 1 T and 2 T.
conclusionsThe minimally invasive implanted TNS device was shown to be effective in inhibiting the micturition reflex under physiologic conditions. Further studies are warranted to determine the inhibitory effects of TNS on nociceptive bladder reflexes.
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