Evidence map›Paper›PMID 32989535›Full record

ArticleSurgical endoscopy2021

Efficacy and safety of colorectal endoscopic submucosal dissection in patients with sarcopenia.

Shungo Goto, Jun Arimoto, Takuma Higurashi, Kota Takahashi, Naoki Ohkubo, Nobuyoshi Kawamura, Tetsuya Tamura, Hisakuni Tomonari, Akito Iwasaki, Leo Taniguchi and 4 more

Abstract read
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In one paragraph

Article in Surgical endoscopy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.1field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Impact of Sarcopenia on Elderly Patients Undergoing Endoscopic Resection: Scoping Review.Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society · 2026
    Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Shungo GotoDepartment of Gastroenterology, Hiratsuka City Hospital, Hiratsuka, Japan.
Jun ArimotoDepartment of Gastroenterology, Omori Red Cross Hospital, Tokyo, Japan.
Takuma HigurashiDepartment of Gastroenterology and Hepatology, Yokohama City University School of Medicine, 3-9 Fukuura, Kanazawa-ku, Yokohama, 236-0004, Japan.
Kota TakahashiDepartment of Gastroenterology, Hiratsuka City Hospital, Hiratsuka, Japan.
Naoki OhkuboDepartment of Gastroenterology, Hiratsuka City Hospital, Hiratsuka, Japan.
Nobuyoshi KawamuraDepartment of Gastroenterology, Hiratsuka City Hospital, Hiratsuka, Japan.
Tetsuya TamuraDepartment of Gastroenterology, Hiratsuka City Hospital, Hiratsuka, Japan.
Hisakuni TomonariDepartment of Gastroenterology, Hiratsuka City Hospital, Hiratsuka, Japan.
Akito IwasakiDepartment of Gastroenterology, Hiratsuka City Hospital, Hiratsuka, Japan.
Leo TaniguchiDepartment of Gastroenterology, Hiratsuka City Hospital, Hiratsuka, Japan.
Hideyuki ChibaDepartment of Gastroenterology, Omori Red Cross Hospital, Tokyo, Japan.
Kazuhiro AtsukawaDepartment of Gastroenterology, Hiratsuka City Hospital, Hiratsuka, Japan.
Yusuke SaigusaDepartment of Biostatistics, Yokohama City University School of Medicine, Yokohama, Japan.
Atsushi NakajimaDepartment of Gastroenterology and Hepatology, Yokohama City University School of Medicine, 3-9 Fukuura, Kanazawa-ku, Yokohama, 236-0004, Japan. nakajima-tky@umin.ac.jp.
Hiratsuka City Hospital · JPYokohama City University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEndoscopic submucosal dissection (ESD) for early-stage colorectal cancer (CRC) has become a common and useful treatment. Although sarcopenia has been identified as an independent risk factor for complications after surgery for CRC, whether sarcopenia is also an independent risk factor for complications after colorectal ESD remains to be clarified. The aim of this study was to compare the outcomes of colorectal ESD in patients with and those without sarcopenia.

methodsThis is a retrospective cohort study. A total of 334 patients underwent colorectal ESD for 361 neoplasms at Hiratsuka City Hospital from March 2012 to October 2018. The neoplasms were divided into two groups depending on the presence or absence of sarcopenia in the patients.

resultsOverall, 334 patients underwent colorectal ESD for 361 neoplasms during the study period. We excluded 90 patients (90 neoplasms), and 244 patients (277 neoplasms) were included in the final analysis (134 from the sarcopenia group, 137 from the non-sarcopenia group). The en-bloc resection rate was high and was not significantly different between the sarcopenia group [126/134 (94.1%)] and the non-sarcopenia group [133/137 (97.1%)], P = 0.1778). The rate of perforation and the rate of delayed bleeding were not significantly different between the sarcopenia group and the non-sarcopenia group [6/134 (4.5%) vs. 9/137 (6.6%), P = 0.314, 4/134 (3%) vs. 6/137 (4.4%), P = 0.3885, respectively].

conclusionsThe presence of sarcopenia did not influence the rate of complications after ESD. Colorectal ESD is safe and effective even in patients with sarcopenia. Prospective multicenter studies are necessary to confirm our results.

Indexed as

Colorectal NeoplasmsEndoscopic Mucosal ResectionSarcopeniaHumansProspective StudiesRetrospective StudiesTreatment OutcomeColorectal neoplasmsEndoscopic submucosal dissectionSarcopenia

Identifiers

PMID32989535
OpenAlexW3089773527

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.