Evidence map›Paper›PMID 32989524›Full record

ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2021

Diagnostic accuracy of patient-reported dry mouth as a predictor for oral dryness in terminally ill cancer patients.

Maiko Shimosato, Keita Asai, Naosuke Yokomichi, Keiji Nagano, Naoki Sakane

Abstract read
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In one paragraph

Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
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  5. Oral dryness and moisture degree at the lingual but not buccal mucosa predict prognosis in end-of-life cancer patients.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Maiko ShimosatoDepartment of Oral and Maxillofacial Surgery, National Hospital Organization Kyoto Medical Center, 1-1, Fukakusa-Mukaihata, Fushimi-Ku, Kyoto, 612-8555, Japan. maikoshimosato0629@hotmail.co.jp.ORCID http://orcid.org/0000-0003-1734-9447
Keita AsaiDepartment of Oral and Maxillofacial Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Naosuke YokomichiDepartment of Palliative and Supportive Care, Seirei Mikatahara General Hospital, Hamamatsu, Japan.
Keiji NaganoDivision of Oral Biology, Health Sciences University of Hokkaido, Hokkaido, Japan.ORCID https://orcid.org/0000-0003-3587-7606
Naoki SakaneDivision of Preventive Medicine, National Hospital Organization Kyoto Medical Center, Kyoto, Japan.
Kyoto Medical Center · JPHealth Sciences University of Hokkaido · JPKyoto University · JPSeirei Mikatabara General Hospital · JP

Funding

Sasakawa Memorial Health Foundation 2017A-008
6 · The paper itself

Abstract

purposeThe aim of the study was to determine the diagnostic accuracy of patient-reported dry mouth using an oral moisture-checking device in terminally ill cancer patients.

methodsThe study was conducted following the STARD guidelines, and the participants were recruited prospectively from the Palliative Care Unit, Kyoto Medical Center, Japan, between 1 January 2017 and 30 November 2018. Patients reporting dry mouth were asked to rate oral dryness on a 5-point rating scale. The outcome was oral dryness at the lingual mucosa, measured using an oral moisture-checking device. Receiver operating characteristic (ROC) curves were plotted, and the sensitivity, specificity, positive and negative predictive values (PPV and NPV), positive and negative likelihood ratios (LR), and overall diagnostic accuracy were calculated.

resultsOf 103 participants, the prevalence of oral dryness was 65.0%. ROC analysis indicated that patient-reported dry mouth was a poor predictor of oral dryness, with an area under the curve of 0.616 (95% confidence interval: 0.508-0.723), a sensitivity of 46.3%, a specificity of 75.8%, a PPV of 55.9%, an NPV of 68.1, a positive LR of 1.9, a negative LR of 0.7, and an overall diagnostic accuracy of 64.1%, with a cut-off value of 3 points.

conclusionIn conclusion, patient-reported dry mouth is not a useful parameter for the assessment of oral dryness in terminally ill cancer patients.

Indexed as

Patient Reported Outcome MeasuresAgedAged, 80 and overCross-Sectional StudiesFemaleHumansMaleNeoplasmsPrevalenceTerminally IllXerostomiaAssessmentDry mouthOral carePalliative carePatient-reported dry mouthThirst

Identifiers

PMID32989524
OpenAlexW3089871101

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.