Evidence map›Paper›PMID 32989410›Full record

ReviewCurrent pathobiology reports2020

Leveraging Computational Modeling to Understand Infectious Diseases.

Adrianne L Jenner, Rosemary A Aogo, Courtney L Davis, Amber M Smith, Morgan Craig

Abstract readReview
In one paragraph

Review in Current pathobiology reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Digital Twins of Biological Systems: A Narrative Review.IEEE open journal of engineering in medicine and biology · 2024
    Article
  8. Article
  9. Natural Products as a Potential Source of Promising Therapeutics for COVID-19 and Viral Diseases.Evidence-based complementary and alternative medicine : eCAM · 2023
    Review
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. Modeling transmission of pathogens in healthcare settings.Current opinion in infectious diseases · 2021
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Adrianne L JennerDepartment of Mathematics and Statistics, Pavillon André-Aisenstadt, Université de Montréal, Montréal, QC H3C 3J7 Canada.
Rosemary A AogoDepartment of Pediatrics, University of Tennessee Health Science Centre, Memphis, USA.
Courtney L DavisNatural Science Division, Pepperdine University, Malibu, USA.
Amber M SmithDepartment of Pediatrics, University of Tennessee Health Science Centre, Memphis, USA.
Morgan CraigDepartment of Mathematics and Statistics, Pavillon André-Aisenstadt, Université de Montréal, Montréal, QC H3C 3J7 Canada.ORCID 0000-0003-4852-4770

Funding

Predictive Modeling of Influenza-Pneumococcal CoinfectionR01AI139088 · NIAID · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI SMITH, AMBER M · 2018 to 2022
$2.1M
NIAID NIH HHS R01 AI139088
6 · The paper itself

Abstract

purpose of reviewComputational and mathematical modeling have become a critical part of understanding in-host infectious disease dynamics and predicting effective treatments. In this review, we discuss recent findings pertaining to the biological mechanisms underlying infectious diseases, including etiology, pathogenesis, and the cellular interactions with infectious agents. We present advances in modeling techniques that have led to fundamental disease discoveries and impacted clinical translation. RECENT

findingsCombining mechanistic models and machine learning algorithms has led to improvements in the treatment of SUMMARY: Computational modeling is now more than ever at the forefront of infectious disease research due to the COVID-19 pandemic. This review highlights how infectious diseases can be better understood by connecting scientists from medicine and molecular biology with those in computer science and applied mathematics.

Indexed as

BacteriaComputational modelingInfectious diseasesMathematicsParasitesViruses

Identifiers

PMID32989410
PMCPMC7511257

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.