ArticleEthnicity & disease2020
Risk Factors for Alzheimer's Disease and Related Dementia Diagnoses in American Indians.
Article in Ethnicity & disease, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.
- Risk, protective, and biomarkers of dementia in Indigenous peoples: A systematic review.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Pooled it
- Alzheimer's disease and related dementias and related health conditions among American Indian and Alaska Native Medicare beneficiaries.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Self-efficacy as a mediator between dementia knowledge and screening intention among American Indian adults.Innovation in aging · 2026Article
- Alzheimer's disease and related dementia diagnoses among American Indian and Alaska Native adults aged ≥45 years, Indian Health Service System, 2016-2020.Journal of the American Geriatrics Society · 2024Article
- Cognitive Impairment and Social Determinants of Health Among Indigenous Women.The Gerontologist · 2024Article
- Increased community engagement of Indigenous Peoples in dementia research leads to higher context relevance of results.Dementia (London, England) · 2024Review
- Promoting diverse perspectives: Addressing health disparities related to Alzheimer's and all dementias.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Article
- Alzheimer's disease and its related dementias in US Native Americans: A major public health concern.Ageing research reviews · 2023Review
- Dementia Risk Models in an Australian First Nations Population: Cross-Sectional Associations and Preparation for Follow-Up.Journal of Alzheimer's disease reports · 2023Article
- Wisconsin Healthcare Utilization Cost Among American Indians/Alaska Natives with and without Alzheimer's Disease and Related Dementias.Journal of Alzheimer's disease : JAD · 2023Article
- Article
- Cardiometabolic Conditions and All-Cause Dementia Among American Indian and Alaska Native People.The journals of gerontology. Series A, Biological sciences and medical sciences · 2022Article
- Vascular cognitive impairment and dementia: An early career researcher perspective.Alzheimer's & dementia (Amsterdam, Netherlands) · 2022Article
- Exploring the Impact of Social Connection Dimensions on Cognitive Impairment in Older Adults: Observational Cohort Study.Inquiry : a journal of medical care organization, provision and financingObservational
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
Abstract
The burden of Alzheimer's disease and related dementias (ADRD) has increased substantially in the United States, particularly in health disparity populations. Little is known about the epidemiology of ADRD in American Indian (AI) adults, although they have a high prevalence of ADRD risk factors including hypertension, diabetes, obesity, and smoking. Using electronic health records from a large health care organization during 2016-18, we describe characteristics of AI patients aged ≥55 years with and without an ADRD diagnosis, assess ADRD risk factors and contrast findings with results from age- and sex-matched non-Hispanic White (NHW) patients. To identify factors associated with ADRD diagnoses, we estimated population-averaged prevalence rate ratios to approximate relative risk (RR) using generalized estimating equations models adjusted for age, sex, and marital and rural residency status. The age-adjusted prevalence of ADRD diagnosis was 6.6% of AI patients, compared with 4.4% in NHW patients. Patient age and diagnosis of hypertension, depression, hyperlipidemia, or diabetes were significantly associated with higher risk of ADRD diagnosis in AIs (RR range: 1.1-2.8) whereas female sex or being married/having a partner were associated with lower risk of ADRD diagnosis (each RR=.7). ADRD risk factors were generally similar between AI and NHW patients, except for sex and marital status. However, the adjusted risk of ADRD was approximately 49% higher in AI patients. To our knowledge, our study is the first to examine ADRD diagnoses and comorbidities in AIs across a large geographical region in southwest United States. Future efforts to confirm our findings in diverse AI communities are warranted.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.