ArticleNature genetics2020
Haplotype-resolved genome analyses of a heterozygous diploid potato.
Article in Nature genetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 143 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
143 citing papers in PubMed.
- The highly heterozygous European amphioxus (Branchiostoma lanceolatum) at the edge of panmixia.PLoS genetics · 2026Article
- Haplotype-resolved regulation of secondary metabolism in cannabis.Horticulture research · 2026Article
- StCYP90C1 modulates plant architecture via regulating brassinosteroid biosynthesis in potato.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Article
- Unveiling the potential regulatory functions of long non-coding RNAs in potato tuberization through integrated analysis of transcriptomics and phytohormone profiles.BMC plant biology · 2026Article
- Synergistic genomic design and thermal processing mitigate anti-nutritional constraints to enhance the nutritional efficacy of diploid potatoes.NPJ science of food · 2026Article
- A chromosome-level genome assembly of Solanum brevicaule (PI 473011) Y1-5, a wild potato relative with robust resistance to potato cyst nematodes.The plant genome · 2026Article
- Haplotype-resolved telomere-to-telomere assembly and haplotype-aware annotation pipeline enable high-quality reannotation of threeHorticulture research · 2026Article
- A rare glycoalkaloid biosynthetic pathway from wild potato unlocks genetic routes to Colorado potato beetle resistance.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Resequencing elucidates the genetic mechanism underlying elite early-maturing potato parent Kexin23.BMC plant biology · 2026Article
- BacPhase: Long-insert paired-end sequencing for bin marker construction and genome phasing.aBIOTECH · 2026Article
- Allele-specific chromatin dynamics underpin heterosis and shoot development in hybrid poplar 'Nanlin895'.Plant molecular biology · 2026Article
- The Camellia sinensis var. sinensis cv. Fuding Dabaicha genome unveils structural variation-driven metabolic innovation.Nature communications · 2026Article
- Identification of genome size and heterozygosity in 510 Jujube (Frontiers in plant science · 2026Article
- Inbreeding depression in diploid potato: genetic basis, deleterious load, and breeding mitigation.Frontiers in plant science · 2026Review
- Flow Cytometry and K-mer-Based Approach for Genome Size Estimation of Clusterbean: A Case Study.Methods in molecular biology (Clifton, N.J.) · 2026Article
- Article
- Chromosome-level haplotype-resolved assembly of highly heterozygous grass genomes with PhaseGrass.Nature communications · 2025Article
- Review
- Tomato and its relatives are breaking the genomics barriers.Journal of experimental botany · 2025Review
- Cytoplasmic and Nuclear Effects on Agronomic Traits in Diploid Interspecific Potato Hybrids.International journal of molecular sciences · 2025Article
83 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Potato (Solanum tuberosum L.) is the most important tuber crop worldwide. Efforts are underway to transform the crop from a clonally propagated tetraploid into a seed-propagated, inbred-line-based hybrid, but this process requires a better understanding of potato genome. Here, we report the 1.67-Gb haplotype-resolved assembly of a diploid potato, RH89-039-16, using a combination of multiple sequencing strategies, including circular consensus sequencing. Comparison of the two haplotypes revealed ~2.1% intragenomic diversity, including 22,134 predicted deleterious mutations in 10,642 annotated genes. In 20,583 pairs of allelic genes, 16.6% and 30.8% exhibited differential expression and methylation between alleles, respectively. Deleterious mutations and differentially expressed alleles were dispersed throughout both haplotypes, complicating strategies to eradicate deleterious alleles or stack beneficial alleles via meiotic recombination. This study offers a holistic view of the genome organization of a clonally propagated diploid species and provides insights into technological evolution in resolving complex genomes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.