Evidence map›Paper›PMID 32989319›Full record

ReviewNature methods2020

Advances and challenges for fluorescence nanothermometry.

Jiajia Zhou, Blanca Del Rosal, Daniel Jaque, Seiichi Uchiyama, Dayong Jin

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature methods, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 129 papers.

0numbers the graph read from it
0cells of the map it votes in
129citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

129 citing papers in PubMed.

  1. Temperature-Driven Emission Redistribution of YbAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
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  9. Sensing with (One or Many) Upconverting Nanoparticles.Accounts of chemical research · 2026
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  15. Review
  16. Tailoring the emission color in SmScientific reports · 2026
    Article
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  18. Review
  19. Building like a Coral-Parallelized, Multiscale Biofabrication.Advanced materials (Deerfield Beach, Fla.) · 2026
    Review
  20. Article

69 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jiajia ZhouInstitute for Biomedical Materials & Devices (IBMD), Faculty of Science, University of Technology Sydney, Sydney, Australia. jiajia.zhou@uts.edu.au.ORCID http://orcid.org/0000-0002-0605-5745
Blanca Del RosalARC Centre of Excellence for Nanoscale Biophotonics, RMIT University, Melbourne, Australia.ORCID http://orcid.org/0000-0001-9174-8097
Daniel JaqueNanobiology Group, Instituto Ramón y Cajal de Investigación Sanitaria, IRYCIS, Madrid, Spain. daniel.jaque@uam.es.ORCID http://orcid.org/0000-0002-3225-0667
Seiichi UchiyamaGraduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan.
Dayong JinInstitute for Biomedical Materials & Devices (IBMD), Faculty of Science, University of Technology Sydney, Sydney, Australia.ORCID http://orcid.org/0000-0003-1046-2666

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fluorescent nanothermometers can probe changes in local temperature in living cells and in vivo and reveal fundamental insights into biological properties. This field has attracted global efforts in developing both temperature-responsive materials and detection procedures to achieve sub-degree temperature resolution in biosystems. Recent generations of nanothermometers show superior performance to earlier ones and also offer multifunctionality, enabling state-of-the-art functional imaging with improved spatial, temporal and temperature resolutions for monitoring the metabolism of intracellular organelles and internal organs. Although progress in this field has been rapid, it has not been without controversy, as recent studies have shown possible biased sensing during fluorescence-based detection. Here, we introduce the design principles and advances in fluorescence nanothermometry, highlight application achievements, discuss scenarios that may lead to biased sensing, analyze the challenges ahead in terms of both fundamental issues and practical implementations, and point to new directions for improving this interdisciplinary field.

Indexed as

FluorescenceAnimalsCellsNanotechnologyThermometry

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.