Evidence map›Paper›PMID 32989085›Full record

ArticleJournal of bacteriology2020

Transcriptional Responses of Pseudomonas aeruginosa to Inhibition of Lipoprotein Transport by a Small Molecule Inhibitor.

Christian Lorenz, Thomas J Dougherty, Stephen Lory

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of bacteriology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. ThemBio · 2026
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Christian LorenzDepartment of Microbiology, Blavatnik Institute, Harvard Medical School, Boston, Massachusetts, USA.
Thomas J DoughertyDepartment of Microbiology, Blavatnik Institute, Harvard Medical School, Boston, Massachusetts, USA.
Stephen LoryDepartment of Microbiology, Blavatnik Institute, Harvard Medical School, Boston, Massachusetts, USA stephen_lory@hms.harvard.edu.ORCID 0000-0002-4079-5229
Harvard University · US

Funding

Genetically-encoded fluorescent RNA sensors for measuring transport of antibiotics into the cytoplasm of Gram-negative pathogens and development of efflux pump inhibitorsR01AI136789 · NIAID · HARVARD MEDICAL SCHOOL · PI LORY, STEPHEN · 2018 to 2022
$3.6M
NIAID NIH HHS R01 AI136789
6 · The paper itself

Abstract

Lipoprotein transport from the inner to the outer membrane, carried out by the Lol machinery, is essential for the biogenesis of the Gram-negative cell envelope and, consequently, for bacterial viability. Recently, small molecule inhibitors of the Lol system in

Indexed as

Anti-Bacterial AgentsBacterial Outer Membrane ProteinsGene Expression Regulation, BacterialLipoproteinsProtein TransportPseudomonas aeruginosaTranscription, GeneticAnti-Bacterial AgentsBacterial Outer Membrane ProteinsLipoproteinslipoprotein transportLolCDEmolecular inhibitorPseudomonastranscriptome

Identifiers

PMID32989085
PMCPMC7685553
OpenAlexW3090517469

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.