Evidence map›Paper›PMID 32989040›Full record

ArticleJournal of cell science2020

Smoothened receptor signaling regulates the developmental shift of GABA polarity in rat somatosensory cortex.

Quentin Delmotte, Mira Hamze, Igor Medina, Emmanuelle Buhler, Jinwei Zhang, Yesser H Belgacem, Christophe Porcher

Open access · hybridAbstract read
In one paragraph

Article in Journal of cell science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Neuronal KActa pharmacologica Sinica · 2024
    Review
  4. Review
  5. Article
  6. A Potent Antagonist of Smoothened in Hedgehog Signaling for Epilepsy.International journal of molecular sciences · 2022
    Article
  7. Article
  8. Review
  9. Review
  10. When Are Depolarizing GABAergic Responses Excitatory?Frontiers in molecular neuroscience · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Quentin DelmotteAix-Marseille University, Parc Scientifique de Luminy, 13273, Marseille, France.
Mira HamzeAix-Marseille University, Parc Scientifique de Luminy, 13273, Marseille, France.
Igor MedinaAix-Marseille University, Parc Scientifique de Luminy, 13273, Marseille, France.ORCID 0000-0001-6839-5414
Emmanuelle BuhlerINSERM (Institut National de la Santé et de la Recherche Médicale) Unité 1249, Marseille, Parc Scientifique de Luminy, 13273 Marseille, France.
Jinwei ZhangInstitute of Biomedical and Clinical Sciences, Medical School, College of Medicine and Health, University of Exeter, Hatherly Laboratories, Exeter EX4 4PS, UK.
Yesser H BelgacemINSERM (Institut National de la Santé et de la Recherche Médicale) Unité 1249, Marseille, Parc Scientifique de Luminy, 13273 Marseille, France.ORCID 0000-0002-9280-4465
Christophe PorcherAix-Marseille University, Parc Scientifique de Luminy, 13273, Marseille, France christophe.porcher@inserm.fr.ORCID 0000-0002-6026-6367
Inserm · FRUniversity of Exeter · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sonic hedgehog (Shh) and its patched-smoothened receptor complex control a variety of functions in the developing central nervous system, such as neural cell proliferation and differentiation. Recently, Shh signaling components have been found to be expressed at the synaptic level in the postnatal brain, suggesting a potential role in the regulation of synaptic transmission. Using

Indexed as

Hedgehog ProteinsSomatosensory CortexAnimalsgamma-Aminobutyric AcidPatched ReceptorsRatsSmoothened Receptorgamma-Aminobutyric AcidHedgehog ProteinsPatched ReceptorsSmoothened ReceptorChloride homeostasisGABAergic transmissionKCC2Smoothened receptorSonic hedgehog

Identifiers

PMID32989040
PMCPMC7595691
OpenAlexW3089057777

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.