Evidence map›Paper›PMID 32989002›Full record

ArticleJournal of lipid research2020

Nuclear translocation ability of Lipin differentially affects gene expression and survival in fed and fasting

Stephanie E Hood, Xeniya V Kofler, Quiyu Chen, Judah Scott, Jason Ortega, Michael Lehmann

Open access · hybridAbstract read
In one paragraph

Article in Journal of lipid research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 20 citations in OpenAlex.

  1. Transcriptional Control of Lipid Metabolism.Advances in experimental medicine and biology · 2026
    Review
  2. Article
  3. Late-life shift in caloric intake affects fly metabolism and longevity.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Stephanie E HoodDepartment of Biological Sciences, University of Arkansas, Fayetteville, AR, USA.
Xeniya V KoflerDepartment of Biological Sciences, University of Arkansas, Fayetteville, AR, USA.
Quiyu ChenDepartment of Biological Sciences, University of Arkansas, Fayetteville, AR, USA.
Judah ScottDepartment of Biological Sciences, University of Arkansas, Fayetteville, AR, USA.
Jason OrtegaDepartment of Biological Sciences, University of Arkansas, Fayetteville, AR, USA.
Michael LehmannDepartment of Biological Sciences, University of Arkansas, Fayetteville, AR, USA. Electronic address: mlehmann@uark.edu.
University of Arkansas at Fayetteville · US

Funding

Nuclear and Endocrine Roles of Lipin in the Control of Metabolism, Growth, and DevelopmentR15DK114748 · NIDDK · UNIVERSITY OF ARKANSAS AT FAYETTEVILLE · PI LEHMANN, MICHAEL · 2017 to 2017
$431k
NIDDK NIH HHS R15 DK114748
6 · The paper itself

Abstract

Lipins are eukaryotic proteins with functions in lipid synthesis and the homeostatic control of energy balance. They execute these functions by acting as phosphatidate phosphatase enzymes in the cytoplasm and by changing gene expression after translocation into the cell nucleus, in particular under fasting conditions. Here, we asked whether nuclear translocation and the enzymatic activity of

Indexed as

Cell NucleusDrosophila ProteinsFastingPhosphatidate PhosphataseActive Transport, Cell NucleusAnimalsDrosophila melanogasterGene Expression RegulationDrosophila ProteinsLpin protein, DrosophilaPhosphatidate Phosphataseenergy metabolismfeeding behaviorgenomic starvation responseimmune responsemetabolic health

Identifiers

PMID32989002
PMCPMC7707171
OpenAlexW3091278704

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.