Evidence map›Paper›PMID 32988990›Full record

ReviewDisease models & mechanisms2020

Neonatal and infant immunity for tuberculosis vaccine development: importance of age-matched animal models.

Laylaa Ramos, Joan K Lunney, Mercedes Gonzalez-Juarrero

Open access · goldAbstract readReview
In one paragraph

Review in Disease models & mechanisms, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. The Ability of Neonatal Mice to Develop Immunity toJournal of cellular immunology · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Frontiers in veterinary science · 2023
    Article
  8. Article
  9. The Year of the Rabbit and the COVID Pandemic.Asia-Pacific journal of public health · 2023
    Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Laylaa RamosMycobacteria Research Laboratories, Microbiology Immunology and Pathology Department, Colorado State University, 1682 Campus Delivery, Fort Collins, CO 80523, USA.
Joan K LunneyAnimal Parasitic Diseases Laboratory, BARC, NEA, ARS, USDA Building 1040, Room 103, Beltsville, MD 20705, USA.
Mercedes Gonzalez-JuarreroMycobacteria Research Laboratories, Microbiology Immunology and Pathology Department, Colorado State University, 1682 Campus Delivery, Fort Collins, CO 80523, USA mercedes.gonzalez-juarrero@colostate.edu.ORCID 0000-0002-4045-2365
Colorado State University · USAgricultural Research Service · US

Funding

Minipigs as animal model for infant TB and vaccine efficacyR21AI111168 · NIAID · COLORADO STATE UNIVERSITY · PI GONZALEZ-JUARRERO, MERCEDES · 2014 to 2015
$470k
NIAID NIH HHS R21 AI111168
6 · The paper itself

Abstract

Neonatal and infant immunity differs from that of adults in both the innate and adaptive arms, which are critical contributors to immune-mediated clearance of infection and memory responses elicited during vaccination. The tuberculosis (TB) research community has openly admitted to a vacuum of knowledge about neonatal and infant immune responses to

Indexed as

ImmunityAgingAnimalsBCG VaccineDisease Models, AnimalHumansInfantInfant, NewbornTuberculosis VaccinesVaccinationBCG VaccineTuberculosis VaccinesImmunityNeonatalTuberculosisVaccines

Identifiers

PMID32988990
PMCPMC7520460
OpenAlexW3087669991

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.