Evidence map›Paper›PMID 32988824›Full record

ArticleAntimicrobial agents and chemotherapy2020

Lysophosphatidylcholine Potentiates Antibacterial Activity of Polymyxin B.

Jitender Yadav, Sana Ismaeel, Ayub Qadri

Open access · greenAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Jitender YadavHybridoma Laboratory, National Institute of Immunology, New Delhi, India.
Sana IsmaeelHybridoma Laboratory, National Institute of Immunology, New Delhi, India.
Ayub QadriHybridoma Laboratory, National Institute of Immunology, New Delhi, India ayub@nii.ac.in.ORCID 0000-0001-5870-8034
National Institute of Immunology · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polymyxin B, used to treat infections caused by antibiotic-resistant Gram-negative bacteria, produces nephrotoxicity at its current dosage. We show that a combination of nonbactericidal concentration of this drug and lysophosphatidylcholine (LPC) potently inhibits growth of

Indexed as

Anti-Bacterial AgentsLysophosphatidylcholinesPolymyxin BGram-Negative BacteriaMicrobial Sensitivity TestsAnti-Bacterial AgentsLysophosphatidylcholinesPolymyxin Bantibiotic resistancelysophosphatidylcholinepolymyxin B

Identifiers

PMID32988824
PMCPMC7674032
OpenAlexW3089881053

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.