Evidence map›Paper›PMID 32988724›Full record

ArticleNutrition, metabolism, and cardiovascular diseases : NMCD2020

The obesity paradox: Analysis from the SMAtteo COvid-19 REgistry (SMACORE) cohort.

Simona Biscarini, Marta Colaneri, Serena Ludovisi, Elena Seminari, Teresa C Pieri, Pietro Valsecchi, Ilaria Gallazzi, Emanuele Giusti, Calogero Cammà, Valentina Zuccaro and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in Nutrition, metabolism, and cardiovascular diseases : NMCD, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 4 pooled it
1.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 4 syntheses or guidelines pooled it, 64 citations in OpenAlex.

  1. Obesity as an independent risk factor for COVID-19 severity and mortality.The Cochrane database of systematic reviews · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Simona BiscariniDivision of Infectious Diseases I, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Marta ColaneriDivision of Infectious Diseases I, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Serena LudovisiDivision of Infectious Diseases II and Immunology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy; Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy.
Elena SeminariDivision of Infectious Diseases I, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Teresa C PieriDivision of Infectious Diseases I, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Pietro ValsecchiDivision of Infectious Diseases I, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Ilaria GallazziDivision of Infectious Diseases I, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Emanuele GiustiCatholic University of Milan, Department of Psychology, Milan, Italy; Istituto Auxologico Italiano IRCCS, Psychology Research Laboratory, San Giuseppe Hospital, Verbania, Italy.
Calogero CammàSection of Gastroenterology and Hepatology, PROMISE, University of Palermo, Palermo, Italy.
Valentina ZuccaroDivision of Infectious Diseases I, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Mario U MondelliDivision of Infectious Diseases II and Immunology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy; Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy. Electronic address: mario.mondelli@unipv.it.
Istituti di Ricovero e Cura a Carattere Scientifico · ITPoliclinico San Matteo Fondazione · ITUniversity of Milan · ITUniversity of Palermo · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsObesity has been suggested as a possible risk factor for a more severe course of COVID-19; however, conclusive evidence is lacking and few studies have investigated the role of BMI as a risk factor for admission to intensive care unit (ICU) and mortality. We retrospectively analyzed a COVID-19 cohort recruited during the first 40 days of the epidemic in Italy. We examined the association between obesity and 30-day mortality, admission to ICU, mortality and length of hospital stay in patients with COVID-19. METHODS AND

resultsDemographic, clinical and outcome data were retrospectively analyzed in 331 patients with COVID-19 admitted to hospital between 21 February and 31 March 2020. The predictive effect of obesity on mortality was assessed using a Cox proportional-hazard regression model, its effect on ICU admission and mortality in the ICU using logistic regressions, and its effect on length of hospital stay using a linear regression. Seventy-four of 331 patients had a BMI ≥30 kg/m

conclusionsObese patients with COVID-19 were more likely to be admitted to ICU than non-obese patients. However, there were no significant differences in mortality between the two groups.

Indexed as

BetacoronavirusAgedAged, 80 and overCoronavirus InfectionsCOVID-19C-Reactive ProteinFemaleHumansIntensive Care UnitsLength of StayMaleMiddle AgedObesityPandemicsPneumonia, ViralProportional Hazards ModelsC-Reactive ProteinBMICOVID-19ICUObesitySARS-CoV-2Severe disease

Identifiers

PMID32988724
PMCPMC7418787
OpenAlexW3047921479

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.