ArticlePoultry science2020
Improvac immunocastration affects the development of thigh muscles but not pectoral muscles in male chickens.
Article in Poultry science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 13 citations in OpenAlex.
- Immunocastration with recombinant GnRH6-CRM197 fusion protein improves reproductive suppression and meat tenderness in roosters.Poultry science · 2026Article
- Different Approaches to Caponisation of Cockerels and Their Relation to Welfare.Animals : an open access journal from MDPI · 2026Article
- Integrative analysis of the transcriptome, proteomics and metabolomics reveals key genes involved in the regulation of breast muscle metabolites in capons.BMC genomics · 2024Article
- Integrated metabolomics and transcriptomics analyses reveal the key genes regulating differential metabolites of longissimus dorsi muscle in castrated South Sichuan black goats (Capra hircus).Functional & integrative genomics · 2023Article
- GnRH-immunocastration: an alternative method for male animal surgical castration.Frontiers in veterinary science · 2023Review
- Hyperpigmentation Inhibits Early Skeletal Muscle Development in Tengchong Snow Chicken Breed.Genes · 2022Article
- Assessment the effect of genomic selection and detection of selective signature in broilers.Poultry science · 2022Article
- Leydig Cells in Immunocastrated Polish Landrace Pig Testis: Differentiation Status and Steroid Enzyme Expression Status.International journal of molecular sciences · 2022Article
- Effects of Caponization on Growth Performance and Carcass Composition of Yangzhou Ganders.Animals : an open access journal from MDPI · 2022Article
- Mild infection induced by low-dose LPS does not impair follicular development and is beneficial to pregnancy in mice.Frontiers in veterinary science · 2022Article
- Detection of Local Tissue Reactions after Anti-GnRF Injection in Male Pigs Assessed Using Magnetic Resonance Imaging.Animals : an open access journal from MDPI · 2021Article
Corrections and comments
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Authors and funding
11 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Improvac has been tentatively used to immune-castrate roosters. The aim of this study was to investigate whether Improvac affected skeletal muscle development in chickens. The muscle fiber type and size and the expression levels of genes related to muscle development in pectoral and thigh muscles were examined at 5, 9, and 14 wk of age in the control, early, late, and early + late Improvac-treated groups. Immunocastration with Improvac affected the development of thigh muscles and the expression of MYH1B, MSTN, and SM. The cross-sectional area in the early group was significantly larger than in the control group at the 14th week (P < 0.01). At the fifth week, the expression levels of MYH1B, MYOD, and MSTN in the early group were significantly higher than those in the control group (P < 0.05), and at the ninth week, the expression level of SM1 in the control group was significantly lower than that in early and late groups (P < 0.05). Immunocastration did not affect pectoral muscle development or the expression of genes related to muscle development.
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