ArticlePoultry science2020
Dynamic distribution of gut microbiota during embryonic development in chicken.
Article in Poultry science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
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Who cites it
37 citing papers in PubMed, 65 citations in OpenAlex.
- Mechanisms of probiotic action in poultry gut: Colonization resistance, bioactive metabolites, quorum sensing activity, and immunomodulation.Poultry science · 2026Review
- Enumeration of organisms occurring in the intestinal tract and yolk sac of day-old chicks from commercial hatcheries.Veterinary research communications · 2026Article
- Host genetic and environmental determinants of chicken gut microbiota: A review.Poultry science · 2026Review
- Probiotic application to hatching egg surface supports microbiota development and acquisition in broiler embryos and hatchlings.Poultry science · 2025Article
- Intestinal microbiota composition and bile salt hydrolase activity in fast and slow growing broiler chickens: implications for growth performance and production efficiency.Journal of animal science and biotechnology · 2025Article
- Article
- Recent advances in the application of microbiota transplantation in chickens.Journal of animal science and biotechnology · 2025Review
- Shift of Microbiota and Modulation of Resistome in the Ceca of Broiler Chicken Fed Berry Pomace Alone or in Combination of a Multienzyme Mixture.Microorganisms · 2025Article
- Effects of Embryonic Thermal Manipulation on Body Performance and Cecum Microbiome in Broiler Chickens Following a Post-Hatch Lipopolysaccharide Challenge.Animals : an open access journal from MDPI · 2025Article
- Effects of litter exposure and flock age of broiler breeders on hatchability and the microbial composition of eggshells, egg membranes, and egg contents.Frontiers in veterinary science · 2025Article
- The developmental changes of fecal microbial composition and diversity in emu (Frontiers in microbiology · 2025Article
- Metabolic modelling uncovers the complex interplay between fungal probiotics, poultry microbiomes, and diet.Microbiome · 2024Article
- In ovo sodium butyrate administration differentially impacts growth performance, intestinal barrier function, immune response, and gut microbiota characteristics in low and high hatch-weight broilers.Journal of animal science and biotechnology · 2024Article
- Effect of In Ovo Supplementation of Slab51 Probiotic Mixture, Associated with Marek's Disease Vaccine, on Growth Performance, Intestinal Morphology andAnimals : an open access journal from MDPI · 2024Article
- Chronological dynamics of the gut microbiome in response to the pasture grazing system in geese.Microbiology spectrum · 2024Article
- A metagenomic investigation of the faecal RNA virome structure of asymptomatic chickens obtained from a commercial farm in Durban, KwaZulu-Natal province, South Africa.BMC genomics · 2024Article
- Exploring the complexities of poultry respiratory microbiota: colonization, composition, and impact on health.Animal microbiome · 2024Review
- Effect of in ovo feeding of xylobiose and xylotriose on plasma immunoglobulin, cecal metabolites production, microbial ecology, and metabolic pathways in broiler chickens.Journal of animal science and biotechnology · 2024Article
- Nearly (?) sterile avian egg in a passerine bird.FEMS microbiology ecology · 2024Article
- Establishment and maturation of gut microbiota in White King pigeon squabs: role of pigeon milk.Frontiers in microbiology · 2024Article
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Authors and funding
12 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The gut microbiota is a complex ecological community and widely recognized in many aspects of research, but little is known on the relation between gut microbiota and embryonic development in chickens. The aim of this study was to explore the dynamic distribution of gut microbiota in chickens' embryos during stages of developments (chicken embryos that had incubated until day 3 [E3], day 12 [E12], and day 19 [E19]). Here, 16S rRNA gene sequencing was performed on the gut microbiota in chicken embryos across different developmental stages. Twenty-one phyla and 601 genera were present in chicken embryos, and 96 genera such as Ochrobactrum, Phyllobacterium, and Amycolatopsis were the core microbiota in the 3 stages of development. Second, 94 genera of microbes were found to change significantly between E3 and E12, and 143 genera significantly differed between E12 and E19 in chicken embryos (P < 0.05). Ochrobactrum and Amycolatopsis decreased with growth changes: E3 (30.4%), E12 (25.1%), and E19 (13.6%) and E3 (11.5%), E12 (7.4%), and E19 (5.6%), respectively. Contrarily, Phyllobacterium increased to 47.9% at E19, indicating the growing trend of microbial diversity among the embryos' development. Moreover, the principal component analysis showed a high level of similarities between E3 and E12 compared with E19, whereas the alpha analysis showed more diversity of gut microbiota at E19. Furthermore, the functional predictions showed that metabolic pathways such as energy metabolism and genetic information processing were significantly enriched on day 3 and day 12 in our study, suggesting their strong influence on growth, development, and immunity of chicken embryos. Our findings provide insights into the understanding of dynamic shifts of gut microbiota during chicken embryonic growth.
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