Evidence map›Paper›PMID 32988541›Full record

ArticlePoultry science2020

Dietary supplementation of total flavonoids from Rhizoma Drynariae improves bone health in older caged laying hens.

J Huang, X F Tong, Z W Yu, Y P Hu, L Zhang, Y Liu, Z X Zhou

Open access · goldAbstract read
In one paragraph

Article in Poultry science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 25 citations in OpenAlex.

  1. Total flavonoids fromAnimal nutrition (Zhongguo xu mu shou yi xue hui) · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Tartary Buckwheat Flavonoids and 25-Hydroxyvitamin DAnimals : an open access journal from MDPI · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. The Interaction between Feed Bioactive Compounds and Chicken Genome.Animals : an open access journal from MDPI · 2023
    Review
  11. Review
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

J HuangKey Lab of Agricultural Animal Genetics, Breeding and Reproduction of Ministry of Education, Department of Animal Nutrition and Feed Science, College of Animal Sciences & Technology, Huazhong Agricultural University, Wuhan 430070, China; The Cooperative Innovation Center for Sustainable Pig Production, Huazhong Agricultural University, Wuhan 430070, China.
X F TongKey Lab of Agricultural Animal Genetics, Breeding and Reproduction of Ministry of Education, Department of Animal Nutrition and Feed Science, College of Animal Sciences & Technology, Huazhong Agricultural University, Wuhan 430070, China; The Cooperative Innovation Center for Sustainable Pig Production, Huazhong Agricultural University, Wuhan 430070, China.
Z W YuKey Lab of Agricultural Animal Genetics, Breeding and Reproduction of Ministry of Education, Department of Animal Nutrition and Feed Science, College of Animal Sciences & Technology, Huazhong Agricultural University, Wuhan 430070, China; The Cooperative Innovation Center for Sustainable Pig Production, Huazhong Agricultural University, Wuhan 430070, China.
Y P HuKey Lab of Agricultural Animal Genetics, Breeding and Reproduction of Ministry of Education, Department of Animal Nutrition and Feed Science, College of Animal Sciences & Technology, Huazhong Agricultural University, Wuhan 430070, China; The Cooperative Innovation Center for Sustainable Pig Production, Huazhong Agricultural University, Wuhan 430070, China.
L ZhangKey Lab of Agricultural Animal Genetics, Breeding and Reproduction of Ministry of Education, Department of Animal Nutrition and Feed Science, College of Animal Sciences & Technology, Huazhong Agricultural University, Wuhan 430070, China; The Cooperative Innovation Center for Sustainable Pig Production, Huazhong Agricultural University, Wuhan 430070, China.
Y LiuExperimental Teaching Center, College of Animal Sciences & Technology, Huazhong Agricultural University, Wuhan 430070, China.
Z X ZhouKey Lab of Agricultural Animal Genetics, Breeding and Reproduction of Ministry of Education, Department of Animal Nutrition and Feed Science, College of Animal Sciences & Technology, Huazhong Agricultural University, Wuhan 430070, China; The Cooperative Innovation Center for Sustainable Pig Production, Huazhong Agricultural University, Wuhan 430070, China. Electronic address: zhongxinzhou@mail.hzau.edu.cn.
Huazhong Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Caged layer osteoporosis (CLO) is a common bone metabolism diseases and poses a great threat to the production of laying hens. So far, there is no effective nutrition intervention to prevent CLO. The objective of this study was to evaluate the effects of dietary total flavonoids from Rhizoma Drynariae (TFRD), a Chinese herbal, on bone health, egg quality, and serum antioxidant capacity of caged laying hens. A total of two hundred sixteen, 54-wk-old Lohmann Pink-shell laying hens at were allocated to 3 groups with 6 replicates of 12 hens per replicate. The control group was fed a basal diet (BD) and 2 treatment groups additionally supplied with 0.5 or 2.0 g/kg TFRD, respectively. Results showed that supplying 2.0 g/kg TFRD enhanced the activities of serum total antioxidant capacity (P < 0.01) and glutathione peroxidase (P < 0.05) and had higher femur and tibia bone mineral density (both P < 0.05) compared with the control group. Dietary 2.0 g/kg TFRD also reduced the activities of serum alkaline phosphatase (P < 0.01), tartrate resistant acid phosphatase (P < 0.01), and the contents of osteocalcin (P < 0.01). Furthermore, tibia histomorphology observation showed that the microstructure of bone tissue was improved after TFRD treatment. Egg quality was not affected by TFRD while the egg weight significantly increased (P < 0.01). These findings suggested that TFRD has beneficial effects on bone health in older caged laying hens.

Indexed as

Bone and BonesChickensDietary SupplementsPolypodiaceaeAnimal FeedAnimalsBone DensityDietFemaleFlavonoidsFlavonoidsbone metabolismlaying henosteoporosistotal flavonoids of Rhizoma Drynariae

Identifiers

PMID32988541
PMCPMC7598317
OpenAlexW3042375585

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.