ArticleeLife2020
Unexplained repeated pregnancy loss is associated with altered perceptual and brain responses to men's body-odor.
Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 15 citations in OpenAlex.
- A large-scale heterogeneous 3D magnetic resonance brain imaging dataset for self-supervised learning.Scientific data · 2026Article
- Mapping of uterine-related neurons in central nervous system of mice byBiochemistry and biophysics reports · 2026Article
- Male Body Odor Affects Emotional State, LH, and Cortisol Secretion in Women of Different Age Groups.Brain sciences · 2024Article
- The Bruce effect: Representational stability and memory formation in the accessory olfactory bulb of the female mouse.Cell reports · 2022Article
- There is chemistry in social chemistry.Science advances · 2022Article
- An olfactory self-test effectively screens for COVID-19.Communications medicine · 2022Article
- Possible Use of Phytochemicals for Recovery from COVID-19-Induced Anosmia and Ageusia.International journal of molecular sciences · 2021Review
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20 authors at 3 institutions in 1 country.
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Abstract
Mammalian olfaction and reproduction are tightly linked, a link less explored in humans. Here, we asked whether human unexplained repeated pregnancy loss (uRPL) is associated with altered olfaction, and particularly altered olfactory responses to body-odor. We found that whereas most women with uRPL could identify the body-odor of their spouse, most control women could not. Moreover, women with uRPL rated the perceptual attributes of men's body-odor differently from controls. These pronounced differences were accompanied by an only modest albeit significant advantage in ordinary, non-body-odor-related olfaction in uRPL. Next, using structural and functional brain imaging, we found that in comparison to controls, most women with uRPL had smaller olfactory bulbs, yet increased hypothalamic response in association with men's body-odor. These findings combine to suggest altered olfactory perceptual and brain responses in women experiencing uRPL, particularly in relation to men's body-odor. Whether this link has any causal aspects to it remains to be explored.
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Registered trials
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