Evidence map›Paper›PMID 32988431›Full record

GuidelineEpidemiology and infection2020

Alcohol-based hand sanitisers as first line of defence against SARS-CoV-2: a review of biology, chemistry and formulations.

D Singh, K Joshi, A Samuel, J Patra, N Mahindroo

Abstract readGuidelineReview
In one paragraph

Guideline in Epidemiology and infection, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
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  7. Review
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  13. Biorisk Management Features of a Temporary COVID-19 Hospital.Applied biosafety : journal of the American Biological Safety Association · 2023
    Article
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  17. Antiviral Properties ofPathogens (Basel, Switzerland) · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

D SinghSchool of Health Sciences, University of Petroleum and Energy Studies, Energy Acres, Bidholi, Via Premnagar, Dehradun248007, Uttarakhand, India.
K JoshiDepartment of Biotechnology, BJM School of Biosciences, Indian Institute of Technology Madras, Chennai, 600036, India.
A SamuelDepartment of Morphology, Surgery and Experimental Medicine, Universita'Degli Studi di Ferrara, Via Savonarola, 9, 44121Ferrara, FE, Italy.
J PatraSchool of Health Sciences, University of Petroleum and Energy Studies, Energy Acres, Bidholi, Via Premnagar, Dehradun248007, Uttarakhand, India.
N MahindrooSchool of Health Sciences, University of Petroleum and Energy Studies, Energy Acres, Bidholi, Via Premnagar, Dehradun248007, Uttarakhand, India.ORCID 0000-0002-3611-7388

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The pandemic due to Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has emerged as a serious global public health issue. Since the start of the outbreak, the importance of hand-hygiene and respiratory protection to prevent the spread of the virus has been the prime focus for infection control. Health regulatory organisations have produced guidelines for the formulation of hand sanitisers to the manufacturing industries. This review summarises the studies on alcohol-based hand sanitisers and their disinfectant activity against SARS-CoV-2 and related viruses. The literature shows that the type and concentration of alcohol, formulation and nature of product, presence of excipients, applied volume, contact time and viral contamination load are critical factors that determine the effectiveness of hand sanitisers.

Indexed as

AlcoholsBetacoronavirusCoronavirusCoronavirus InfectionsCOVID-19Drug ContaminationHand SanitizersHumansPandemicsPneumonia, ViralSARS-CoV-2AlcoholsHand SanitizersAlcohol rubsCOVID-19encapsulated virusesethanolhand sanitiserisopropanolSARS-CoV-2

Identifiers

PMID32988431
PMCPMC7550876

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.