ArticleBMC pediatrics2020
Accelerated skeletal maturation is associated with overweight and obesity as early as preschool age: a cross-sectional study.
Article in BMC pediatrics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Distinguishing central precocious puberty from nonprogressive breast development: adiposity and DXA body composition.Journal of the Endocrine Society · 2026Article
- Correlation of body mass index and serum 25-hydroxyvitamin D levels with advanced bone age in children from northwest China: a cross-sectional study.Translational pediatrics · 2026Article
- Childhood Obesity and Craniofacial Growth: A Cross-Sectional Orthodontic Cephalometric Study.Medicina (Kaunas, Lithuania) · 2026Article
- Updating radiographic parameters for the healthy growing hip: are current parameters still valid?Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology · 2026Article
- Two Sides of a Coin: Molecular, metabolic, and Phenotypic Convergence in Pediatric Undernutrition and Obesity.Current obesity reports · 2026Review
- Odds of Developing Overweight or Obesity Increase with Height Decile in Tall Healthy Weight Kindergarteners: Longitudinal Results from the West Virginia Coronary Artery Risk Detection In Appalachian Communities (WV CARDIAC) Project.Journal of pediatrics. Clinical practice · 2026Article
- Independence of the body composition index from nutritional status affecting bone maturation.Pediatric research · 2026Article
- Adrenal androgen mediates the association between obesity and accelerated skeletal maturation in children and adolescents.Frontiers in endocrinology · 2026Article
- Anti-Müllerian Hormone Levels Are Associated With Skeletal Maturity in Adolescent Girls: A Longitudinal Study.Health science reports · 2025Article
- The correlation between insulin-like growth factor 1 and left ventricular mass index in obese children.BMC endocrine disorders · 2025Article
- Article
- Body composition trajectories during childhood predict skeletal maturation at puberty: A longitudinal study.Heliyon · 2024Article
- Association between sex hormones and bone age in boys aged 9-18 years from China.Journal of cellular and molecular medicine · 2024Article
- Growth in height and its association with overweight and obesity in Mexican children: an evaluation based on a nationally representative sample (ENSANUT 2018).Frontiers in public health · 2024Article
- Ultrasound and Clinical Alterations in the Foot of Children with Obesity and Diabetes.Diagnostics (Basel, Switzerland) · 2023Article
- Altered IGF-I activity and accelerated bone elongation in growth plates precede excess weight gain in a mouse model of juvenile obesity.Journal of applied physiology (Bethesda, Md. : 1985) · 2022Article
- Anatomical changes in vertebra in dystrophic scoliosis due to neurofibromatosis and its implications on surgical safety.Spine deformity · 2022Article
- An Approach to the Evaluation and Management of the Obese Child With Early Puberty.Journal of the Endocrine Society · 2022Review
- Chronological and Skeletal Age in Relation to Physical Fitness Performance in Preschool Children.Frontiers in pediatrics · 2021Article
- Bone age in prepubertal children with nonfamilial or familial idiopathic short stature and prepubertal short-stature children born small for gestational age: a longitudinal data analysis.Clinical pediatric endocrinology : case reports and clinical investigations : official journal of the Japanese Society for Pediatric Endocrinology · 2021Article
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6 authors.
Funding
Abstract
backgroundBody mass index (BMI) and skeletal age (SA) are important indicators of individual growth and maturation. Although the results have not been unified, most studies indicated that accelerated skeletal maturation is associated with overweight/obesity. However, there have so far been insufficient studies about the association between accelerated skeletal maturation and overweight/obesity in preschoolers, particularly Asian children. A cross-sectional study was conducted on Chinese children to verify the association between accelerated skeletal maturation and overweight/obesity at preschool age.
methodsThe study involved 1330 participants aged 3.1-6.6 years old (730 males and 600 females) in Shanghai, China. The skeletal age was determined according to the method of TW3-C RUS. Accelerated skeletal maturation was defined as relative SA (SA minus chronological age [CA]) ≥1.0 years. BMI was classified as thinness, normal weight, overweight, and obesity according to the International Obesity Task Force (IOTF) BMI cut-offs. The Chi-square was performed to determine the statistically significant difference in the frequency of accelerated skeletal maturation in BMI and age categories. The logistic regression model analyzed the association between accelerated skeletal maturation and overweight/obesity.
resultsThe percentage of accelerated skeletal maturation increased with BMI (7.8% of children in thinness group had accelerated skeletal maturation; the percentage increased to 30.8% in obese group. x
conclusionsThere is an association between accelerated skeletal maturation and overweight/obesity among preschool children. This study suggests that accelerated skeletal maturation might coexist with overweight/obesity in preschool children, and interventions, such as dietary modifications and increasing levels of physical activity, should be employed to prevent both accelerated skeletal maturation and overweight/obesity as early as preschool age.
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