Evidence map›Paper›PMID 32988293›Full record

ArticleTissue engineering. Part C, Methods2020

Success Criteria and Preclinical Testing of Multifunctional Hydrogels for Tendon Regeneration.

Ryan C Locke, Eden M Ford, Karin G Silbernagel, April M Kloxin, Megan L Killian

Abstract read
In one paragraph

Article in Tissue engineering. Part C, Methods, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Interfacial Tissue Regeneration with Bone.Current osteoporosis reports · 2024
    Review
  6. Review
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ryan C LockeDepartment of Biomedical Engineering, University of Delaware, Newark, Delaware, USA.
Eden M FordDepartment of Chemical and Biomolecular Engineering, University of Delaware, Newark, Delaware, USA.
Karin G SilbernagelDepartment of Physical Therapy, University of Delaware, Newark, Delaware, USA.
April M KloxinDepartment of Chemical and Biomolecular Engineering, University of Delaware, Newark, Delaware, USA.
Megan L KillianDepartment of Biomedical Engineering, University of Delaware, Newark, Delaware, USA.

Funding

This renovation project will create over 1455 sq. ft. of state- of-the-art reseaP20GM104316 · NIGMS · UNIVERSITY OF DELAWARE · PI SCHMITZ, KARL ROBERT · 2014 to 2024
$26.8M
Pilot Research Subproject ProgramP30GM110758 · NIGMS · UNIVERSITY OF DELAWARE · PI PATEL, SANDEEP · 2014 to 2018
$5.8M
NIGMS NIH HHS P20 GM104316NIGMS NIH HHS P30 GM110758
6 · The paper itself

Abstract

Tendon injuries are difficult to heal, in part, because intrinsic tendon healing, which is dominated by scar tissue formation, does not effectively regenerate the native structure and function of healthy tendon. Further, many current treatment strategies also fall short of producing regenerated tendon with the native properties of healthy tendon. There is increasing interest in the use of cell-instructive strategies to limit the intrinsic fibrotic response following injury and improve the regenerative capacity of tendon

Indexed as

Materials TestingAnimalsBiomechanical PhenomenaCell LineFemaleHumansHydrogelsPolymerizationRats, Long-EvansRegenerationTendon InjuriesTendonsHydrogelscollagen mimetic peptideshydrogelsin situ photopolymerizationmultifunctional synthetic biomaterialspreclinical translationtendon injury modelstherapeutic strategies

Identifiers

PMID32988293
PMCPMC7869878

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.