Evidence map›Paper›PMID 32988273›Full record

ArticleChannels (Austin, Tex.)2020

Charged pore-lining residues are required for normal channel kinetics in the eukaryotic mechanosensitive ion channel MSL1.

Angela M Schlegel, Elizabeth S Haswell

Open access · goldAbstract read
In one paragraph

Article in Channels (Austin, Tex.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Angela M SchlegelDepartment of Biology, Washington University , St. Louis, Missouri, USA.ORCID 0000-0001-5253-5769
Elizabeth S HaswellDepartment of Biology, Washington University , St. Louis, Missouri, USA.
Washington University in St. Louis · US

Funding

Howard Hughes Medical Institute
6 · The paper itself

Abstract

Mechanosensitive (MS) ion channels are widespread mechanisms for cellular mechanosensation that can be directly activated by increasing membrane tension. The well-studied MscS family of MS ion channels is found in bacteria, archaea, and plants. MscS-Like (MSL)1 is localized to the inner mitochondrial membrane of

Indexed as

Mechanical PhenomenaAmino Acid SequenceArabidopsis ProteinsBiomechanical PhenomenaEscherichia coliIon Channel GatingIon ChannelsKineticsModels, MolecularMutationPorosityProtein Conformation, alpha-HelicalProtein TransportArabidopsis ProteinsAT4G00290 protein, ArabidopsisIon ChannelsArabidopsis thalianagiant E. coli spheroplastsmechanosensitive ion channelMSL1patch-clamp electrophysiology

Identifiers

PMID32988273
PMCPMC7757850
OpenAlexW3089785276

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.