Evidence map›Paper›PMID 32988218›Full record

ArticleCirculation. Heart failure2020

Sex Disparities in the Management and Outcomes of Cardiogenic Shock Complicating Acute Myocardial Infarction in the Young.

Saraschandra Vallabhajosyula, Lina Ya'Qoub, Mandeep Singh, Malcolm R Bell, Rajiv Gulati, Wisit Cheungpasitporn, Pranathi R Sundaragiri, Virginia M Miller, Allan S Jaffe, Bernard J Gersh and 2 more

Open access · greenAbstract readComparative Study
In one paragraph

Article in Circulation. Heart failure, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 2 pooled it
7.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 2 syntheses or guidelines pooled it, 125 citations in OpenAlex.

  1. SCAI/EAPCI/ACVC Expert Consensus Statement on Cardiogenic Shock in Women.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2025
    Guideline
  2. Pooled it
  3. Sex disparities in revascularization strategies and mortality in infarct-related cardiogenic shock.Clinical research in cardiology : official journal of the German Cardiac Society · 2026
    Article
  4. The Blind Spot in Cardiogenic Shock: Patients Beyond the Current Paradigm.Journal of the Society for Cardiovascular Angiography & Interventions · 2026
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Saraschandra VallabhajosyulaDepartment of Cardiovascular Medicine (S.V., M.S., M.R.B., R.G., A.S.J., B.J.G., D.R.H., G.W.B.), Mayo Mayo Clinic, Rochester, MN.
Lina Ya'QoubDivision of Cardiovascular Medicine, Department of Medicine, Louisiana State University School of Medicine, Shreveport (L.Y.).
Mandeep SinghDepartment of Cardiovascular Medicine (S.V., M.S., M.R.B., R.G., A.S.J., B.J.G., D.R.H., G.W.B.), Mayo Mayo Clinic, Rochester, MN.
Malcolm R BellDepartment of Cardiovascular Medicine (S.V., M.S., M.R.B., R.G., A.S.J., B.J.G., D.R.H., G.W.B.), Mayo Mayo Clinic, Rochester, MN.
Rajiv GulatiDepartment of Cardiovascular Medicine (S.V., M.S., M.R.B., R.G., A.S.J., B.J.G., D.R.H., G.W.B.), Mayo Mayo Clinic, Rochester, MN.
Wisit CheungpasitpornDivision of Nephrology, Department of Medicine, University of Mississippi School of Medicine, Jackson (W.C.).
Pranathi R SundaragiriDivision of Hospital Internal Medicine, Department of Medicine (P.R.S.), Mayo Mayo Clinic, Rochester, MN.
Virginia M MillerDepartment of Physiology and Biomedical Engineering (V.M.M.), Mayo Mayo Clinic, Rochester, MN.
Allan S JaffeDepartment of Cardiovascular Medicine (S.V., M.S., M.R.B., R.G., A.S.J., B.J.G., D.R.H., G.W.B.), Mayo Mayo Clinic, Rochester, MN.
Bernard J GershDepartment of Cardiovascular Medicine (S.V., M.S., M.R.B., R.G., A.S.J., B.J.G., D.R.H., G.W.B.), Mayo Mayo Clinic, Rochester, MN.
David R HolmesDepartment of Cardiovascular Medicine (S.V., M.S., M.R.B., R.G., A.S.J., B.J.G., D.R.H., G.W.B.), Mayo Mayo Clinic, Rochester, MN.
Gregory W BarsnessDepartment of Cardiovascular Medicine (S.V., M.S., M.R.B., R.G., A.S.J., B.J.G., D.R.H., G.W.B.), Mayo Mayo Clinic, Rochester, MN.
Mayo Clinic · USLouisiana State University in Shreveport · USUniversity of Mississippi Medical Center · US

Funding

Mayo Clinic Center for Translational Science ActivitiesUL1TR000135 · NCATS · MAYO CLINIC ROCHESTER · PI KHOSLA, SUNDEEP · 2012 to 2015
$41.2M
NCATS NIH HHS UL1 TR000135
6 · The paper itself

Abstract

backgroundThere are limited data on how sex influences the outcomes of acute myocardial infarction-cardiogenic shock (AMI-CS) in young adults.

methodsA retrospective cohort of AMI-CS admissions aged 18 to 55 years, during 2000 to 2017, was identified using the National Inpatient Sample. Use of coronary angiography, percutaneous coronary intervention, mechanical circulatory support and noncardiac interventions was identified. Outcomes of interest included in-hospital mortality, use of cardiac interventions, hospitalization costs, and length of stay.

resultsA total 90 648 AMI-CS admissions ≤55 years of age were included, of which 26% were women. Higher rates of CS were noted in men (2.2% in 2000 to 4.8% in 2017) compared with women (2.6% in 2000 to 4.0% in 2017;

conclusionsIn young AMI-CS admissions, women are treated less aggressively and experience higher in-hospital mortality than men.

Indexed as

Healthcare DisparitiesAdolescentAdultAge FactorsDatabases, FactualFemaleHospital MortalityHumansInpatientsMaleMiddle AgedMyocardial InfarctionPatient AdmissionRace FactorsRetrospective StudiesRisk Assessmentadultfemaleodds ratioshock, cardiogenicyoung adult

Identifiers

PMID32988218
PMCPMC7578068
OpenAlexW3090822636

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.