ArticleInternational journal of oral science2017
Quaternary ammonium-induced multidrug tolerant Streptococcus mutans persisters elevate cariogenic virulence in vitro.
Article in International journal of oral science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 33 citations in OpenAlex.
- [Chlorhexidine and Polident Induce the Formation ofSichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2026Article
- The Effect of Different Organic Acids and Their Combination on the Cell Barrier and Biofilm ofFoods (Basel, Switzerland) · 2023Article
- Antibiotic Tolerance Indicative of Persistence Is Pervasive among Clinical Streptococcus pneumoniae Isolates and Shows Strong Condition Dependence.Microbiology spectrum · 2022Article
- AntisenseInternational journal of nanomedicine · 2022Article
- Novel dental implant modifications with two-staged double benefits for preventing infection and promoting osseointegrationBioactive materials · 2021Article
- Review
- Dental Restorative Materials for Elderly Populations.Polymers · 2021Review
- Inactivation of Multi-Drug Resistant Non-TyphoidalPathogens (Basel, Switzerland) · 2020Article
- Regulating Oral Biofilm from Cariogenic State to Non-Cariogenic State via Novel Combination of Bioactive Therapeutic Composite and Gene-Knockout.Microorganisms · 2020Article
- Interaction between the Oral Microbiome and Dental Composite Biomaterials: Where We Are and Where We Should Go.Journal of dental research · 2020Article
- Threats to adhesive/dentin interfacial integrity and next generation bio-enabled multifunctional adhesives.Journal of biomedical materials research. Part B, Applied biomaterials · 2019Review
- The inhibitory effect of quaternary ammonium salt on bacteria in root canal.Scientific reports · 2019Article
- ResumptiveFrontiers in microbiology · 2019Article
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Authors and funding
11 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Dental caries are the most prevalent chronic infections in the oral cavity, and Streptococcus mutans acts as the main cariogenic bacterial species. Antibacterial quaternary ammonium compounds (QAs) have been developed to preveFnt or treat dental caries. However, there is no report on the tolerance of S. mutans to QAs. In this study, we investigated the development of S. mutans persistence induced by a novel dental caries defensive agent, dimethylaminododecyl methacrylate (DMADDM), for the first time. Typical biphasic killing kinetics for persisters were observed in both S. mutans planktonic and biofilm cultures challenged by DMADDM at concentrations of 20 and 200 μg·mL
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