Evidence map›Paper›PMID 32987820›Full record

ReviewJournal of clinical medicine2020

Ganglionated Plexi Ablation for the Treatment of Atrial Fibrillation.

Sahar Avazzadeh, Shauna McBride, Barry O'Brien, Ken Coffey, Adnan Elahi, Martin O'Halloran, Alan Soo, Leo R Quinlan

Open access · goldAbstract readReview
In one paragraph

Review in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 1 pooled it
4.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 1 synthesis or guideline pooled it, 56 citations in OpenAlex.

  1. Pooled it
  2. Observational
  3. Article
  4. Review
  5. Review
  6. Review
  7. Review
  8. Review
  9. Short-term deceleration capacity: a novel non-invasive indicator of parasympathetic activity in patients undergoing pulmonary vein isolation.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2025
    Article
  10. Variability of baroreceptor reflex assessed by tilt table test in a patient undergoing pulmonary vein isolation.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2025
    Observational
  11. Review
  12. Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. Review
  18. Overview of Cardiac Arrhythmias and Treatment Strategies.Pharmaceuticals (Basel, Switzerland) · 2023
    Review
  19. Pearls and Pitfalls of Pulsed Field Ablation.Korean circulation journal · 2023
    Review
  20. The ridge line of left pulmonary vein isolation from left atrial appendage can subsequently increase the completion rate of the mitral isthmus block line.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Sahar AvazzadehPhysiology and Human Movement Laboratory, CÚRAM SFI Centre for Research in Medical Devices, School of Medicine, Human biology building, National University of Ireland (NUI) Galway, H91 TK33 Galway, Ireland.ORCID 0000-0001-7705-8970
Shauna McBridePhysiology and Human Movement Laboratory, CÚRAM SFI Centre for Research in Medical Devices, School of Medicine, Human biology building, National University of Ireland (NUI) Galway, H91 TK33 Galway, Ireland.
Barry O'BrienAtriAN Medical Limited, Unit 204, NUIG Business Innovation Centre, Upper Newcastle, H91 TK33 Galway, Ireland.
Ken CoffeyAtriAN Medical Limited, Unit 204, NUIG Business Innovation Centre, Upper Newcastle, H91 TK33 Galway, Ireland.
Adnan ElahiTranslational Medical Devise Lab (TMD Lab), Lambe Institute of Translational Research, University College Hospital Galway, H91 ERW1 Galway, Ireland.ORCID 0000-0003-0988-5776
Martin O'HalloranTranslational Medical Devise Lab (TMD Lab), Lambe Institute of Translational Research, University College Hospital Galway, H91 ERW1 Galway, Ireland.
Alan SooDepartment of Cardiothoracic Surgery, University Hospital Galway, Saolta Hospital HealthCare Group, H91 YR71 Galway, Ireland.
Leo R QuinlanPhysiology and Human Movement Laboratory, CÚRAM SFI Centre for Research in Medical Devices, School of Medicine, Human biology building, National University of Ireland (NUI) Galway, H91 TK33 Galway, Ireland.ORCID 0000-0002-4011-6732
Ollscoil na Gaillimhe – University of Galway · IEUniversity Hospital Galway · IE

Funding

Enterprise Ireland DT20180123
6 · The paper itself

Abstract

Atrial fibrillation (AF) is the most common type of cardiac arrhythmia and is associated with significant morbidity and mortality. The autonomic nervous system (ANS) plays an important role in the initiation and development of AF, causing alterations in atrial structure and electrophysiological defects. The intrinsic ANS of the heart consists of multiple ganglionated plexi (GP), commonly nestled in epicardial fat pads. These GPs contain both parasympathetic and sympathetic afferent and efferent neuronal circuits that control the electrophysiological properties of the myocardium. Pulmonary vein isolation and other cardiac catheter ablation targets including GP ablation can disrupt the fibers connecting GPs or directly damage the GPs, mediating the benefits of the ablation procedure. Ablation of GPs has been evaluated over the past decade as an adjunctive procedure for the treatment of patients suffering from AF. The success rate of GP ablation is strongly associated with specific ablation sites, surgical techniques, localization techniques, method of access and the incorporation of additional interventions. In this review, we present the current data on the clinical utility of GP ablation and its significance in AF elimination and the restoration of normal sinus rhythm in humans.

Indexed as

ablationatrial fibrillationautonomic nervous systemganglionated plexi

Identifiers

PMID32987820
PMCPMC7598705
OpenAlexW3088282852

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.