Evidence map›Paper›PMID 32987671›Full record

ArticleMolecules (Basel, Switzerland)2020

A Bioactive Olive Pomace Extract Prevents the Death of Murine Cortical Neurons Triggered by NMDAR Over-Activation.

Alice Franchi, Marco Pedrazzi, Alessandro Alberto Casazza, Enrico Millo, Gianluca Damonte, Annalisa Salis, Nara Liessi, Franco Onofri, Antonella Marte, Silvia Casagrande and 3 more

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Alice FranchiDepartment of Experimental Medicine (DIMES), University of Genoa, Viale Benedetto XV-1, 16132 Genova, Italy.
Marco PedrazziDepartment of Experimental Medicine (DIMES), University of Genoa, Viale Benedetto XV-1, 16132 Genova, Italy.
Alessandro Alberto CasazzaDepartment of Civil, Chemical and Environmental Engineering, University of Genoa, Pole of Chemical Engineering, via Opera Pia 15, 16145 Genoa, Italy.ORCID 0000-0001-6851-6386
Enrico MilloDepartment of Experimental Medicine (DIMES), University of Genoa, Viale Benedetto XV-1, 16132 Genova, Italy.
Gianluca DamonteDepartment of Experimental Medicine (DIMES), University of Genoa, Viale Benedetto XV-1, 16132 Genova, Italy.ORCID 0000-0001-8769-2051
Annalisa SalisCentre of Excellence for Biomedical Research (CEBR), University of Genoa, Viale Benedetto XV 9, 16132 Genova, Italy.ORCID 0000-0002-3082-2908
Nara LiessiCentre of Excellence for Biomedical Research (CEBR), University of Genoa, Viale Benedetto XV 9, 16132 Genova, Italy.
Franco OnofriDepartment of Experimental Medicine (DIMES), University of Genoa, Viale Benedetto XV-1, 16132 Genova, Italy.
Antonella MarteDepartment of Experimental Medicine (DIMES), University of Genoa, Viale Benedetto XV-1, 16132 Genova, Italy.
Silvia CasagrandeDepartment of Experimental Medicine (DIMES), University of Genoa, Viale Benedetto XV-1, 16132 Genova, Italy.
Roberta De TullioDepartment of Experimental Medicine (DIMES), University of Genoa, Viale Benedetto XV-1, 16132 Genova, Italy.ORCID 0000-0001-6925-3207
Patrizia PeregoDepartment of Civil, Chemical and Environmental Engineering, University of Genoa, Pole of Chemical Engineering, via Opera Pia 15, 16145 Genoa, Italy.
Monica AvernaDepartment of Experimental Medicine (DIMES), University of Genoa, Viale Benedetto XV-1, 16132 Genova, Italy.ORCID 0000-0002-9463-7533
University of Genoa · ITOspedale Policlinico San Martino · IT

Funding

Università degli Studi di Genova FRA 2018, FRA 2019
6 · The paper itself

Abstract

We have recently demonstrated that bioactive molecules, extracted by high pressure and temperature from olive pomace, counteract calcium-induced cell damage to different cell lines. Here, our aim was to study the effect of the same extract on murine cortical neurons, since the preservation of the intracellular Ca

Indexed as

AnimalsBiflavonoidsCalcium SignalingCatechinCell DeathCells, CulturedMiceNeuronsN-MethylaspartateOleaPlant ExtractsProanthocyanidinsReceptors, N-Methyl-D-AspartateBiflavonoidsCatechinN-MethylaspartatePlant ExtractsProanthocyanidinsprocyanidin B2Receptors, N-Methyl-D-Aspartatecalcium homeostasiscalpainneuron primary cultureNMDARolive pomace extractproanthocyanidins

Identifiers

PMID32987671
PMCPMC7839963
OpenAlexW3087888450

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.