Evidence map›Paper›PMID 32987319›Full record

SynthesisSleep medicine reviews2021

Efficacy of cognitive behavioral therapy for insomnia in breast cancer: A meta-analysis.

Yan Ma, Daniel L Hall, Long H Ngo, Qingqing Liu, Paul A Bain, Gloria Y Yeh

Open access · greenAbstract readMeta-AnalysisReview
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Sleep medicine reviews, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 80 papers, 12 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
80citing papers in PubMed, 12 pooled it
15.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

80 citing papers in PubMed, 12 syntheses or guidelines pooled it, 145 citations in OpenAlex.

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  6. A systematic review and meta-analysis of music interventions to improve sleep in adults with mental health problems.European psychiatry : the journal of the Association of European Psychiatrists · 2024
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  9. Representation of race and ethnicity among cancer survivors in trials of cognitive behavioral therapy for insomnia (CBT-I): A systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Pooled it
  10. For whom and what outcomes does cognitive-behavioral-therapy work among cancer survivors: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
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  16. Effects of Tai Chi Chuan on physical function and health in breast cancer patients.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
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20 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Yan MaDivision of Interdisciplinary Medicine and Biotechnology, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States; Osher Center for Integrative Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States. Electronic address: dr.yan.ma@gmail.com.
Daniel L HallMassachusetts General Hospital, Harvard Medical School, Boston, MA, United States.
Long H NgoDivision of General Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States; Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, United States.
Qingqing LiuDivision of Interdisciplinary Medicine and Biotechnology, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States; Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China.
Paul A BainCountway Library of Medicine, Harvard Medical School, Boston, MA, United States.
Gloria Y YehOsher Center for Integrative Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States; Division of General Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States.
Beth Israel Deaconess Medical Center · USBrigham and Women's Hospital · USHarvard University · US

Funding

Research Training in Complementary and Integrative MedicineT32AT000051 · NCCIH · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI GLORIA Y YEH · 1999 to 2026
$10.2M
Mentoring and Patient-Oriented Research in Mind-Body ExerciseK24AT009465 · NCCIH · BETH ISRAEL DEACONESS MEDICAL CENTER · PI GLORIA Y YEH · 2017 to 2026
$1.3M
A Multimodal Mind-Body Intervention for Fear of Recurrence among Cancer SurvivorsK23AT010157 · NCCIH · MASSACHUSETTS GENERAL HOSPITAL · PI HALL, DANIEL LEE · 2019 to 2023
$785k
GINSENG'S EFFECTS ON MRNA PROFILES IN A DIABETES-2 MODELF32AT000051 · NCCIH · UNIVERSITY OF TEXAS AUSTIN · PI PAN, SHUJIA J · 1999 to 2001
$96k
NCCIH NIH HHS F32 AT000051NCCIH NIH HHS K23 AT010157NCCIH NIH HHS K24 AT009465NCCIH NIH HHS T32 AT000051
6 · The paper itself

Abstract

Insomnia is highly prevalent among patients with breast cancer (BC). Although cognitive behavioral therapy for insomnia (CBT-I) is available in integrative oncology settings, it poses unique challenges for BC survivors. Our review aimed to assess the evidence for the therapeutic effects of CBT-I on insomnia in BC. Randomized controlled trials (RCTs) that included patients/survivors with BC and insomnia, and at least one validated self-report measure of sleep quality were included in the review. Of the 14 included RCTs (total N = 1363), the most common components incorporated in CBT-I interventions were sleep hygiene, stimulus control and sleep restriction. Pooled effect sizes favored CBT-I at post-intervention (Hedges' g = -0.779, 95% CI = -0.949, -0.609), short-term follow-up (within six months, Hedges' g = -0.653, 95% CI = -0.808, -0.498), and long-term follow-up (12 mo, Hedges' g = -0.335, 95% CI = -0.532, -0.139). In sub-analyses, CBT-I had similar effect sizes regardless of potential modifiers (comparison design, delivery formats, etc.). As an integrative oncology intervention, CBT-I is efficacious for reducing insomnia and improving sleep quality in women treated for BC, with medium-to-large effect sizes that persist after intervention delivery ends. Given the variability in the CBT-I components tested in RCTs, future studies should investigate the optimal integration of CBT-I components for managing insomnia during BC survivorship.

Indexed as

Breast NeoplasmsCognitive Behavioral TherapySleep Initiation and Maintenance DisordersFemaleHumansSleepSurvivorsTreatment OutcomeBreast cancerCognitive behavioral therapy for insomniaEfficacyMeta-analysisRandomized controlled trial

Identifiers

PMID32987319
PMCPMC8210529
OpenAlexW3084240423

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.