SynthesisGastrointestinal endoscopy2021
Comparison of EUS-guided endoscopic transpapillary and percutaneous gallbladder drainage for acute cholecystitis: a systematic review with network meta-analysis.
Synthesis in Gastrointestinal endoscopy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
47 citing papers in PubMed, 4 syntheses or guidelines pooled it, 99 citations in OpenAlex.
- Pooled it
- Acute cholecystitis management in high-risk, critically ill, and unfit-for-surgery patients: the Italian Society of Emergency Surgery and Trauma (SICUT) guidelines.Updates in surgery · 2024Guideline
- Endoscopic ultrasound (EUS)-guided cholecystostomy versus percutaneous cholecystostomy (PTC) in the management of acute cholecystitis in patients unfit for surgery: a systematic review and meta-analysis.Surgical endoscopy · 2023Pooled it
- Determinants of outcomes of transmural EUS-guided gallbladder drainage: systematic review with proportion meta-analysis and meta-regression.Surgical endoscopy · 2022Pooled it
- Clinical Challenges in Acute Cholecystitis: Endoscopic Drainage Strategies (EUS-GBD vs. ET-GBD) in Patients with Surgical Contraindications.Journal of clinical medicine · 2026Review
- Toward Tailored EUS-Guided Gallbladder Drainage in the Era of Lumen-Apposing Metal Stent.Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society · 2026Article
- Wall stretch sign to prevent trans-gastric lumen apposing metal stent deployment during endoscopic ultrasound-guided gallbladder drainage.Endoscopy · 2026Article
- Evolution of gallbladder drainage: a comprehensive review from percutaneous to endoscopic ultrasound-guided approaches.Journal of gastroenterology · 2026Article
- Endoscopic management of acute cholecystitis in high-risk surgical patients: A comprehensive review article.DEN open · 2026Review
- Endoscopic ultrasound-guided gallbladder drainage for acute cholecystitis: Should the endoscopic option become the status quo?World journal of gastrointestinal pharmacology and therapeutics · 2026Review
- Long-Term Outcomes of Endoscopic Transpapillary Gallbladder Stenting for Symptomatic Cholelithiasis.Gastro hep advances · 2026Article
- The Effect of Lumen-Apposing Metal Stent (LAMS) in Acute Cholecystitis Unfit for Surgery: Good Tidings.Diagnostics (Basel, Switzerland) · 2025Review
- Percutaneous, transpapillary, and transmural drainage in acute cholecystitis: a comparative analysis of techniques, stent selection, and clinical.Annals of medicine and surgery (2012) · 2025Review
- Single-session endoscopic retrograde cholangiopancreatography and endoscopic ultrasound-guided gallbladder drainage for management of biliary obstruction and gallbladder disease.iGIE : innovation, investigation and insights · 2025Article
- Pilot study of a novel lumen-apposing metal stent for endoscopic ultrasound-guided procedures in porcine models.DEN open · 2025Article
- Percutaneous endoscopy-guided gallbladder lumen-apposing metal stent retrieval, lithotripsy, and cholecystoduodenal stenting in a patient with acute cholecystitis.Radiology case reports · 2025Article
- A stent of strength: use of lumen-apposing metal stents (LAMS) for biliary pathologies and other novel applications.Abdominal radiology (New York) · 2025Review
- Age-period-cohort analysis of gallbladder and biliary diseases epidemiological trends from 1990 to 2021 and forecasts for 2035: a systematic analysis from the global burden of disease study 2021.BMC gastroenterology · 2025Article
- Endoscopic ultrasound-guided gallbladder drainage for acute cholecystitis.Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society · 2025Review
- Feasibility of a novel 5F plastic stent in endoscopic transpapillary gallbladder drainage for acute cholecystitis.Endoscopy international open · 2025Article
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimsThe optimal method of gallbladder drainage (GBD) for acute cholecystitis in nonsurgical candidates is uncertain. The aim of the current study was to conduct a network meta-analysis comparing the 3 methods of GBD (percutaneous [PT], endoscopic transpapillary [ETP], and EUS-guided).
methodsA comprehensive literature search for all comparative studies assessing the efficacy of either 2 or all modalities used for treatment of acute cholecystitis in patients at high risk for cholecystectomy was performed. Primary outcomes of technical and clinical success and postprocedure adverse events were assessed. Secondary outcomes were reintervention, unplanned readmissions, recurrent cholecystitis, and mortality.
resultsTen studies were identified, comprising 1267 patients (472 EUS-GBD, 493 PT-GBD, and 302 ETP-GBD). In the network ranking estimate, PT-GBD and EUS-GBD had the highest likelihood of technical success (EUS-GBD vs PT-GBD vs ETP-GBD: 2.00 vs 1.02 vs 2.98) and clinical success (EUS-GBD vs PT-GBD vs ETP-GBD: 1.48 vs 1.55 vs 2.98). EUS-GBD had the lowest risk of recurrent cholecystitis (EUS-GBD vs PT-GBD vs ETP-GBD: 1.089 vs 2.02 vs 2.891). PT-GBD had the highest risk of reintervention (EUS-GBD vs PT-GBD vs ETP-GBD: 1.81 vs 2.99 vs 1.199) and unplanned readmissions (EUS-GBD vs PT-GBD vs ETP-GBD: 1.582 vs 2.944 vs 1.474), whereas ETP-GBD was associated with the lowest rates of mortality (EUS-GBD vs PT-GBD vs ETP-GBD: 2.62 vs 2.09 vs 1.29).
conclusionsThe 3 modalities of GBD have their respective advantages and disadvantages. Selection of technique will depend on available expertise. In centers with expertise in endoscopic GBD, the techniques are preferred over PT-GBD with improved outcomes. (Clinical trial registration number: CRD42020181972.).
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.