ArticleExperimental neurology2021
Acute intermittent hypoxia boosts spinal plasticity in humans with tetraplegia.
Article in Experimental neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- Hypoxic conditioning in Parkinson's disease: randomized controlled multiple N-of-1 trials.Nature communications · 2025Trial
- Efficacy and time course of acute intermittent hypoxia effects in the upper extremities of people with cervical spinal cord injury.Experimental neurology · 2021Trial
- Review
- Maximal strength and voluntary activation of adductor pollicis after a single session of acute intermittent hypercapnia or acute intermittent hypoxia.Experimental physiology · 2026Article
- Article
- Paired corticospinal-motoneuronal stimulation enhances ballistic motor learning and corticospinal plasticity in older adults.The Journal of physiology · 2026Article
- Safety and potential benefits of acute intermittent hypoxia in people with chronic traumatic brain injury.medRxiv : the preprint server for health sciences · 2025Article
- Hypoxia and Tissue Regeneration: Adaptive Mechanisms and Therapeutic Opportunities.International journal of molecular sciences · 2025Review
- Microstructural integrity within the damaged region of the residual corticofugal projection from primary motor cortex predicts the effect of noninvasive neuromodulation targeting the spinal cord in chronic stroke.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025Article
- Intermittent hypoxia-induced enhancements in corticospinal excitability predict gains in motor learning and metabolic efficiency.Scientific reports · 2025Article
- Hebbian priming of human motor learning.Nature communications · 2024Article
- Low level CORespiratory physiology & neurobiology · 2024Article
- Respiratory plasticity following spinal cord injury: perspectives from mouse to man.Neural regeneration research · 2022Review
- Effects of acute intermittent hypoxia on corticospinal excitability within the primary motor cortex.European journal of applied physiology · 2022Article
- Multiple N-of-1 trials to investigate hypoxia therapy in Parkinson's disease: study rationale and protocol.BMC neurology · 2022Article
- The ups and downs of intermittent hypoxia as a therapy for ventilatory insufficiency.The Journal of physiology · 2022Article
- Therapeutic acute intermittent hypoxia: A translational roadmap for spinal cord injury and neuromuscular disease.Experimental neurology · 2022Review
- Ampakine pretreatment enables a single hypoxic episode to produce phrenic motor facilitation with no added benefit of additional episodes.Journal of neurophysiology · 2021Article
- Electrical epidural stimulation of the cervical spinal cord: implications for spinal respiratory neuroplasticity after spinal cord injury.Journal of neurophysiology · 2021Review
- Relevance of carotid bodies in COVID-19: A hypothetical viewpoint.Autonomic neuroscience : basic & clinical · 2021Review
Corrections and comments
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Authors and funding
11 authors.
Funding
Abstract
Paired corticospinal-motoneuronal stimulation (PCMS) elicits spinal synaptic plasticity in humans with chronic incomplete cervical spinal cord injury (SCI). Here, we examined whether PCMS-induced plasticity could be potentiated by acute intermittent hypoxia (AIH), a treatment also known to induce spinal synaptic plasticity in humans with chronic incomplete cervical SCI. During PCMS, we used 180 pairs of stimuli where corticospinal volleys evoked by transcranial magnetic stimulation over the hand representation of the primary motor cortex were timed to arrive at corticospinal-motoneuronal synapses of the first dorsal interosseous (FDI) muscle ~1-2 ms before the arrival of antidromic potentials elicited in motoneurons by electrical stimulation of the ulnar nerve. During AIH, participants were exposed to brief alternating episodes of hypoxic inspired gas (1 min episodes of 9% O
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Registered trials
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