Evidence map›Paper›PMID 32986999›Full record

ArticleJornal de pediatria

Allergic sensitization pattern of patients in Brazil.

Carolina Sanchez Aranda, Renata R Cocco, Felipe F Pierotti, Emanuel Sarinho, Flávio Sano, Arnaldo Porto, Nelson Rosário, Herberto J Chong Neto, Ekaterini Goudouris, Lillian S Moraes and 7 more

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Jornal de pediatria. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

17 authors at 12 institutions in 2 countries.

Carolina Sanchez ArandaUniversidade Federal de São Paulo, Departamento de Pediatria, São Paulo, SP, Brazil. Electronic address: aranda@unifesp.br.
Renata R CoccoUniversidade Federal de São Paulo, Departamento de Pediatria, São Paulo, SP, Brazil.
Felipe F PierottiUniversidade Federal de São Paulo, Departamento de Pediatria, São Paulo, SP, Brazil.
Emanuel SarinhoUniversidade Federal de Pernambuco, Departamento de Pediatria, Recife, PE, Brazil.
Flávio SanoHospital Nipo Brasileiro, Departamento de Pediatria, São Paulo, SP, Brazil.
Arnaldo PortoUniversidade de Passo Fundo, Departamento de Pediatria, Passo Fundo, RS, Brazil.
Nelson RosárioUniversidade Federal do Paraná, Departamento de Pediatria, Curitiba, PR, Brazil.
Herberto J Chong NetoUniversidade Federal do Paraná, Departamento de Pediatria, Curitiba, PR, Brazil.
Ekaterini GoudourisUniversidade Federal do Rio de Janeiro, Departamento de Pediatria, Rio de Janeiro, RJ, Brazil.
Lillian S MoraesUniversidade Federal de Mato Grosso, Departamento de Pediatria, Cuiabá, MT, Brazil.
Neusa F WandalsenFaculdade de Medicina do ABC, Departamento de Pediatria, São Paulo, SP, Brazil.
Marcia C MalloziUniversidade Federal de São Paulo, Departamento de Pediatria, São Paulo, SP, Brazil.
Antônio C PastorinoUniversidade de São Paulo, Departamento de Pediatria, São Paulo, SP, Brazil.
Jackeline M FrancoUniversidade Federal de Sergipe, Departamento de Pediatria, Aracaju, SE, Brazil.
Maria L ChavarriaUniversidade Federal de Goiás, Departamento de Pediatria, Goiânia, GO, Brazil.
Magnus BorresUppsala University, Department of Maternal and Child Health, Uppsala, Sweden.
Dirceu SoléUniversidade Federal de São Paulo, Departamento de Pediatria, São Paulo, SP, Brazil.
Universidade Federal de São Paulo · BRUniversidade Federal do Paraná · BRFaculdade de Medicina do ABC · BRHospital IPO · BRUniversidade de Passo Fundo · BRUniversidade de São Paulo · BRUniversidade Federal de Goiás · BRUniversidade Federal de Mato Grosso · BRUniversidade Federal de Pernambuco · BRUniversidade Federal de Sergipe · BRUniversidade Federal do Rio de Janeiro · BRUppsala University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveAllergic sensitization is one of the key components for the development of allergies. Polysensitization seems to be related to the persistence and severity of allergic diseases. Furthermore, allergic sensitization has a predictive role in the development of allergies. The aim of this study was to characterize the pattern of sensitization of atopic patients treated at different pediatric allergy referral centers in Brazil.

methodsA nation-wide transversal multicenter study collected data on patients attended in Brazil. Peripheral blood samples were collected to determine the serum levels of allergen-specific IgE. If allergen-specific IgE was higher than 0.1 kUA/L, the following specific components were quantified.

resultsA total of 470 individuals were enrolled in the study. Mite sensitization was the most frequent kind in all participants. A high frequency of sensitization to furry animals and grasses featured in the respiratory allergies. Regarding components, there was a predominance of sensitization to Der p 1 and Der p 2. It has been verified that having a food allergy, atopic dermatitis, or multimorbidity are risk factors for the development of more severe allergic disease.

conclusionStudies on the pattern of allergic sensitization to a specific population offer tools for the more effectual prevention, diagnosis, and treatment of allergic diseases. Sensitization to dust mites house was the most prevalent in the evaluated sample. High rates of sensitization to furry animals also stand out. Patients with food allergy, atopic dermatitis, or multimorbidity appear to be at greater risk for developing more severe allergic diseases.

Indexed as

AsthmaAllergensAnimalsBrazilChildHumansImmunoglobulin EPyroglyphidaeAllergensImmunoglobulin EAllergyBiomarkersChildrenPrognosisSensitization

Identifiers

PMID32986999
PMCPMC9432344
OpenAlexW3088769220

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.