Evidence map›Paper›PMID 32986928›Full record

ReviewInternational wound journal2020

Pathophysiology of coronavirus disease 2019 for wound care professionals.

Sammy Al-Benna

Open access · hybridAbstract readReview
In one paragraph

Review in International wound journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. ACE2 gene expression in skin and subcutaneous tissues of free flaps.Chinese journal of traumatology = Zhonghua chuang shang za zhi · 2025
    Article
  3. Review
  4. Article
  5. Article
  6. European journal of breast health · 2021
    Article
  7. Article
  8. Breast reconstruction during the COVID-19 pandemic in resource-limited settings.GMS Interdisciplinary plastic and reconstructive surgery DGPW · 2021
    Review
  9. Angiotensin-converting enzyme 2 gene expression in human male urological tissues: implications for pathogenesis and virus transmission pathways.African journal of urology : the official journal of the Pan African Urological Surgeons' Association (PAUSA) · 2021
    Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Sammy Al-BennaDivision of Plastic and Reconstructive Surgery, Faculty of Medicine and Health Sciences, Stellenbosch University and Tygerberg Academic Hospital, Cape Town, South Africa.ORCID https://orcid.org/0000-0003-4079-9286
Stellenbosch University · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is pressing urgency to understand the pathogenesis of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) which causes Coronavirus disease 2019 (COVID-19). The tissue tropism of SARS-CoV-2 includes not only the lung but also the vascular and integumentary systems. Angiotensin-converting enzyme 2 (ACE2) appears to be the key functional receptor for the virus. There is a prominent innate immune response to SARS-CoV-2 infection, including inflammatory cytokines, chemokines, the complement system, and acute phase proteins. The pathophysiologic significance of SARS-COV-2 and host immune system interaction, and COVID-19-associated coagulopathy instigating microvascular injury syndrome mediated by activation of complement pathways, and an associated procoagulant state is important for wound care professionals to understand.

Indexed as

Health PersonnelImmunity, InnateComorbidityCOVID-19HumansSARS-CoV-2Wounds and Injuriesacute phase proteinsblood coagulation disorderscomplement system proteinsCOVID-19severe acute respiratory syndrome coronavirus 2

Identifiers

PMID32986928
PMCPMC7536990
OpenAlexW3089226570

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.