Evidence map›Paper›PMID 32986476›Full record

ReviewAnnual review of animal biosciences2021

Programmed DNA Elimination in Vertebrates.

Jeramiah J Smith, Vladimir A Timoshevskiy, Cody Saraceno

Open access · bronzeAbstract readReview
In one paragraph

Review in Annual review of animal biosciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
7.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 60 citations in OpenAlex.

  1. Review
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  12. Biparental inheritance of germline-specific chromosomes in the sea lamprey and their roles in oocytes.Proceedings of the National Academy of Sciences of the United States of America · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Jeramiah J SmithDepartment of Biology, University of Kentucky, Lexington, Kentucky 40506, USA; email: jjsmit3@uky.edu, vti224@uky.edu, cody.saraceno@uky.edu.
Vladimir A TimoshevskiyDepartment of Biology, University of Kentucky, Lexington, Kentucky 40506, USA; email: jjsmit3@uky.edu, vti224@uky.edu, cody.saraceno@uky.edu.
Cody SaracenoDepartment of Biology, University of Kentucky, Lexington, Kentucky 40506, USA; email: jjsmit3@uky.edu, vti224@uky.edu, cody.saraceno@uky.edu.
University of Kentucky · US

Funding

Functional Analysis of Programmed Genome RearrangementR35GM130349 · NIGMS · UNIVERSITY OF KENTUCKY · PI Jeramiah James Smith · 2019 to 2026
$2.7M
NIGMS NIH HHS R35 GM130349
6 · The paper itself

Abstract

Over the last few decades, an increasing number of vertebrate taxa have been identified that undergo programmed genome rearrangement, or programmed DNA loss, during development. In these organisms, the genome of germ cells is often reproducibly different from the genome of all other cells within the body. Although we clearly have not identified all vertebrate taxa that undergo programmed genome loss, the list of species known to undergo loss now represents ∼10% of vertebrate species, including several basally diverging lineages. Recent studies have shed new light on the targets and mechanisms of DNA loss and their association with canonical modes of DNA silencing. Ultimately, expansion of these studies into a larger collection of taxa will aid in reconstructing patterns of shared/independent ancestry of programmed DNA loss in the vertebrate lineage, as well as more recent evolutionary events that have shaped the structure and content of eliminated DNA.

Indexed as

AnimalsCell NucleusDNAEvolution, MolecularGenomeGenomic InstabilityVertebratesDNAevolutiongenomeprogrammed DNA lossprogrammed genome rearrangementvertebrate

Identifiers

PMID32986476
PMCPMC8715500
OpenAlexW3091493450

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.