Evidence map›Paper›PMID 32986470›Full record

Trial reportCanadian journal of psychiatry. Revue canadienne de psychiatrie2021

Suicidality Over the First 5 Years of Psychosis: Does Extending Early Intervention Have Benefits?

Srividya N Iyer, Sally S Mustafa, Laura Moro, G Eric Jarvis, Ridha Joober, Sherezad Abadi, Nicola Casacalenda, Howard C Margolese, Amal Abdel-Baki, Martin Lepage and 1 more

Open access · bronzeAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Canadian journal of psychiatry. Revue canadienne de psychiatrie, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Srividya N IyerDepartment of Psychiatry, 5620McGill University, Montreal, Quebec, Canada.ORCID 0000-0001-5367-9086
Sally S MustafaPrevention and Early Intervention Program for Psychosis (PEPP), 26632Douglas Mental Health University Institute, Montreal, Quebec, Canada.ORCID 0000-0003-2439-203X
Laura MoroPrevention and Early Intervention Program for Psychosis (PEPP), 26632Douglas Mental Health University Institute, Montreal, Quebec, Canada.
G Eric JarvisDepartment of Psychiatry, 5620McGill University, Montreal, Quebec, Canada.
Ridha JooberDepartment of Psychiatry, 5620McGill University, Montreal, Quebec, Canada.
Sherezad Abadi26632Douglas Mental Health University Institute, Montreal, Quebec, Canada.
Nicola CasacalendaDepartment of Psychiatry, 5620McGill University, Montreal, Quebec, Canada.
Howard C MargoleseDepartment of Psychiatry, 5620McGill University, Montreal, Quebec, Canada.
Amal Abdel-BakiDepartment of Psychiatry, 5622University of Montreal, Montreal, Quebec, Canada.
Martin LepageDepartment of Psychiatry, 5620McGill University, Montreal, Quebec, Canada.
Ashok MallaDepartment of Psychiatry, 5620McGill University, Montreal, Quebec, Canada.
Douglas Mental Health University Institute · CAJewish General Hospital · CAMcGill University Health Centre · CAUniversité de Montréal · CA

Funding

Early Psychosis in India and Canada: Investigating outcomes and family factorsR01MH093303 · NIMH · MCGILL UNIVERSITY · PI MALLA, ASHOK · 2012 to 2016
$2.3M
CIHR MCT 94189NIMH NIH HHS R01 MH093303
6 · The paper itself

Abstract

objectiveWe aimed to investigate whether individuals with first-episode psychosis (FEP) receiving extended early intervention (EI) were less likely to experience suicidal ideation and behaviors than those transferred to regular care after 2 years of EI. Another objective was to examine the 5-year course of suicidality in FEP.

methodsWe conducted a secondary analysis of a randomized controlled trial where 220 patients were randomized after 2 years of EI to receive extended EI or regular care for the subsequent 3 years. Suicidality was rated using the Brief Psychiatric Rating Scale. Linear mixed model analysis was used to study time and group effects on suicidality.

resultsExtended EI and regular care groups did not differ on suicidality. There was a small decrease in suicidality over time,

conclusionsThe first month of treatment is a critical period for suicide risk in FEP. Although early reductions in suicidality are often maintained, our findings make the case for sustained monitoring for suicide risk management.

Indexed as

Psychotic DisordersSuicideHumansPsychiatric Status Rating ScalesSuicidal Ideationdepressive symptomsearly interventionfirst-episode psychosislongitudinal courseRCTsuicidality

Identifiers

PMID32986470
PMCPMC8107949
OpenAlexW3089855707

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.