Evidence map›Paper›PMID 32986433›Full record

ArticleNano letters2020

Physiologically Relevant Mechanics of Biodegradable Polyester Nanoparticles.

Nourin Alsharif, Behnaz Eshaghi, Björn M Reinhard, Keith A Brown

Open access · greenAbstract read
In one paragraph

Article in Nano letters, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Article
  3. Virus-Mimicking Polymer Nanoparticles Targeting CD169ACS applied materials & interfaces · 2022
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Nourin AlsharifDepartment of Mechanical Engineering, Boston University, Boston, Massachusetts 02215, United States.ORCID 0000-0001-7378-6700
Behnaz EshaghiDepartment of Chemistry and the Photonics Center, Boston University, Boston, Massachusetts 02215, United States.
Björn M ReinhardDepartment of Chemistry and the Photonics Center, Boston University, Boston, Massachusetts 02215, United States.ORCID 0000-0003-2550-5331
Keith A BrownDepartment of Mechanical Engineering, Boston University, Boston, Massachusetts 02215, United States.ORCID 0000-0002-2379-2018
Boston University · US

Funding

GM3 Nanoparticles for Sustained Delivery of Anti-Retrovirals to Lymphatic TissuesR01AI132111 · NIAID · BOSTON UNIVERSITY MEDICAL CAMPUS · PI GUMMULURU, SURYARAM, REINHARD, BJOERN MARKUS · 2018 to 2022
$2.7M
NIAID NIH HHS R01 AI132111
6 · The paper itself

Abstract

Despite the extensive use of biodegradable polyester nanoparticles for drug delivery, and reports of the strong influence of nanoparticle mechanics on nano-bio interactions, there is a lack of systematic studies on the mechanics of these nanoparticles under physiologically relevant conditions. Here, we report indentation experiments on poly(lactic acid) and poly(lactide-

Indexed as

NanoparticlesPolyglycolic AcidLactic AcidParticle SizePolyestersPolylactic Acid-Polyglycolic Acid CopolymerLactic AcidPolyestersPolyglycolic AcidPolylactic Acid-Polyglycolic Acid Copolymerbiodegradable nanoparticlemechanical propertynanoindentationpolyester nanoparticlepolymer nanoparticle

Identifiers

PMID32986433
PMCPMC7834348
OpenAlexW3089723463

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.