Evidence map›Paper›PMID 32986236›Full record

ArticleCardiology journal2022

Leveraging clinical decision support tools to improve guideline-directed medical therapy in patients with atherosclerotic cardiovascular disease at hospital discharge.

Anish Vani, Karen Kan, Eduardo Iturrate, Dina Levy-Lambert, Nathaniel R Smilowitz, Archana Saxena, Martha J Radford, Eugenia Gianos

Open access · goldAbstract read
In one paragraph

Article in Cardiology journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.3field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Anish VaniDepartment of Medicine, NYU Langone Health, New York, United States.
Karen KanDepartment of Medicine, NYU Langone Health, New York, United States.
Eduardo IturrateDepartment of Medicine, NYU Langone Health, New York, United States.
Dina Levy-LambertDepartment of Medicine, NYU Langone Health, New York, United States.
Nathaniel R SmilowitzDepartment of Medicine, NYU Langone Health, New York, United States.
Archana SaxenaDepartment of Medicine, NYU Langone Health, New York, United States.
Martha J RadfordDepartment of Medicine, NYU Langone Health, New York, United States.
Eugenia GianosDepartment of Cardiology, Lenox Hill Hospital, Northwell Health, New York, United States. egianos@northwell.edu.
NYU Langone Health · USNorthwell Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGuidelines recommend moderate to high-intensity statins and antithrombotic agents in patients with atherosclerotic cardiovascular disease (ASCVD). However, guideline-directed medical therapy (GDMT) remains suboptimal.

methodsIn this quality initiative, best practice alerts (BPA) in the electronic health record (EHR) were utilized to alert providers to prescribe to GDMT upon hospital discharge in ASCVD patients. Rates of GDMT were compared for 5 months pre- and post-BPA implementation. Multivariable regression was used to identify predictors of GDMT.

resultsIn 5985 pre- and 5568 post-BPA patients, the average age was 69.1 ± 12.8 years and 58.5% were male. There was a 4.0% increase in statin use from 67.3% to 71.3% and a 3.1% increase in antithrombotic use from 75.3% to 78.4% in the post-BPA cohort.

conclusionsThis simple EHR-based initiative was associated with a modest increase in ASCVD patients being discharged on GDMT. Leveraging clinical decision support tools provides an opportunity to influence provider behavior and improve care for ASCVD patients, and warrants further investigation.

Indexed as

AtherosclerosisCardiovascular DiseasesDecision Support Systems, ClinicalHydroxymethylglutaryl-CoA Reductase InhibitorsAgedAged, 80 and overFemaleFibrinolytic AgentsHospitalsHumansMaleMiddle AgedPatient DischargeTreatment OutcomeFibrinolytic AgentsHydroxymethylglutaryl-CoA Reductase Inhibitorsbest practice alertscardiovascular diseaseclinical decision support toolselectronic health recordsguideline-directed medical therapyoptimal medical therapysecondary prevention

Identifiers

PMID32986236
PMCPMC9550339
OpenAlexW3088993634

What OpenQuestion holds

Texttitle and abstract
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.