Evidence map›Paper›PMID 32986164›Full record

ArticleEuropean journal of applied physiology2020

Hyperthermia and dehydration: their independent and combined influences on physiological function during rest and exercise.

Anne M J van den Heuvel, Benjamin J Haberley, David J R Hoyle, Rodney J Croft, Gregory E Peoples, Nigel A S Taylor

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Article in European journal of applied physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Anne M J van den HeuvelSchool of Medicine, Centre for Human and Applied Physiology, University of Wollongong, Wollongong, NSW, 2522, Australia.
Benjamin J HaberleySchool of Medicine, Centre for Human and Applied Physiology, University of Wollongong, Wollongong, NSW, 2522, Australia.
David J R HoyleSchool of Medicine, Centre for Human and Applied Physiology, University of Wollongong, Wollongong, NSW, 2522, Australia.
Rodney J CroftAustralian Centre for Electromagnetic Bioeffects Research, School of Psychology, Illawarra Health & Medical Research Institute, University of Wollongong, Wollongong, NSW, 2522, Australia.
Gregory E PeoplesSchool of Medicine, Centre for Human and Applied Physiology, University of Wollongong, Wollongong, NSW, 2522, Australia.
Nigel A S TaylorSchool of Medicine, Centre for Human and Applied Physiology, University of Wollongong, Wollongong, NSW, 2522, Australia. nigelastaylor@gmail.com.ORCID http://orcid.org/0000-0002-3655-5249

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis experiment was designed to quantify the independent and combined influences of hyperthermia and dehydration on effector control during rest and exercise.

methodsTo achieve that, whole-body hydration of healthy adults (N = 8) was manipulated into each of three states (euhydrated, 3% and 5% dehydrated), and then clamped within each of two thermal states (normothermia [mean body temperature: 36.1 °C] and moderate hyperthermia [mean body temperature: 38.2 °C]). Those treatment combinations provided six levels of physiological strain, with resting physiological data collected at each level. The effects of isothermal, thermally unclamped and incremental exercise were then investigated in normothermic individuals during each level of hydration.

resultsAt rest, dehydration alone reduced urine flows by 83% (3% dehydrated) and 93% (5% dehydrated), while the reduction accompanying euhydrated hyperthermia was 86%. The sensitivities of renal water conservation to 3% dehydration (-21% mOsm

conclusionIn all instances, the physiological impact of these thermal- and hydration-state stresses was independently expressed, with no evidence of interactive influences. Renal water-conservation was independently and powerfully modified, exposing possible between-treatment differences in sodium reabsorption.

Indexed as

AdultBlood PressureBody TemperatureBody Temperature RegulationDehydrationExerciseFeverHot TemperatureHumansHyperthermiaMaleRestSkinSweatingDehydrationHyperthermiaPlasma volumeSweatingUrine productionVascular conductance

Identifiers

PMID32986164

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.